pls, a gene found in type I staphylococcal cassette chromosome mec (SCCmec) regions of methicillin-resistant Staphylococcus aureus strains, was present in 12 of the 15 human clinical Staphylococcus sciuri isolates studied. Pls was expressed in the S. sciuri isolates, although at a lower level than in S. aureus. Other parts of SCCmec could also be found in the S. sciuri genome.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1081304 | PMC |
| http://dx.doi.org/10.1128/JCM.43.3.1415-1419.2005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: The genetic determinants of peripartum depression (PPD) are not fully understood. Using a multi-polygenic score approach, we characterized the relationship between genome-wide information and the history of PPD in patients with mood disorders, with the hypothesis that multiple polygenic risk scores (PRSs) could potentially influence the development of PPD.
Methods: We calculated 341 PRSs for 178 parous mood disorder inpatients affected by major depressive disorder (MDD) or bipolar disorder (BD) with ( = 62) and without ( = 116) a history of PPD.
Block selection in multiblock partial least squares for modeling genotype-phenotype relations in Saccharomyces.
PLoS One
January 2025
Department of Mathematics and Statistics, Riphah International University, Islamabad, Pakistan.
In data-based modeling, correlations between explanatory variables often lead to the formation of distinct gene blocks. This study focuses on identifying influential gene blocks and key variables within these blocks, with a particular application in mind: genotype-phenotype mapping in Saccharomyces. To overcome the challenges of a limited sample size, we use partial least squares (PLS).
View Article and Find Full Text PDF[Impact of Organic Amendment on the Bacterial Community and Rice Yield in Paddy Soil].
Huan Jing Ke Xue
January 2025
State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China.
In this investigation, the influence of organic amendment on the structural and functional dynamics of soil microbial communities and its effect on rice productivity were examined. Five fertilization treatments from a 40-year field experiment were selected： no fertilizer （CK）, inorganic NPK fertilizer （NPK）, inorganic NPK combined with green manure （NG）, inorganic NPK combined with green manure and pig manure （NGM）, and inorganic NPK combined with green manure and rice straw （NGS）. The findings revealed that the organic amendment enhanced the soil organic carbon （SOC）, total nitrogen （TN）, and total phosphorus （TP） levels, alongside an increase in rice yield； notably, the most significant improvements were observed with the NGM treatment.
View Article and Find Full Text PDFMicrobial functional genes play crucial roles in enhancing soil nutrient availability of halophyte rhizospheres in salinized grasslands.
Sci Total Environ
December 2024
The Research Center of Soil and Water Conservation and Ecological Environment, Chinese Academy of Sciences and Ministry of Education, Yangling, Shaanxi 712100, China; Institute of Soil and Water Conservation, Chinese Academy of Sciences and Ministry of Water Resources, Yangling, Shaanxi 712100, China; State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau, Institute of Soil and Water Conservation, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address:
Land degradation due to salinization threatens ecosystem health. Phytoremediation, facilitated by functional microorganisms, has gained attention for improving saline-alkali soils. However, the relationship between the functional potential of rhizosphere microbes involved in multi-element cycling and soil nutrient pools remain unclear.
View Article and Find Full Text PDFPatterns of genomic instability in > 2000 patients with ovarian cancer across six clinical trials evaluating olaparib.
Genome Med
December 2024
Translational Medicine, Oncology R&D, AstraZeneca, Cambridge Biomedical Campus, 1 Francis Crick Avenue, Cambridge, CB2 0AA, UK.
Background: The introduction of poly(ADP-ribose) polymerase (PARP) inhibitors represented a paradigm shift in the treatment of ovarian cancer. Genomic data from patients with high-grade ovarian cancer in six phase II/III trials involving the PARP inhibitor olaparib were analyzed to better understand patterns and potential causes of genomic instability.
Patients And Methods: Homologous recombination deficiency (HRD) was assessed in 2147 tumor samples from SOLO1, PAOLA-1, Study 19, SOLO2, OPINION, and LIGHT using next-generation sequencing technology.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!