Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10024-004-1002-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical characteristics, management, and malignancy rate of oral lichen planus: a European multicenter study.
J Stomatol Oral Maxillofac Surg
January 2025
Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Introduction: Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous condition that includes a spectrum of oral clinical manifestations ranging from mild painless white lesions to painful erosions and ulcers. The purpose of this European multicenter study is to describe the general characteristics of OLP lesions, the clinical and histopathological diagnosis, and the management of OLP at different European Oral Medicine and Maxillofacial Surgery centers, in order to minimize selections biases and provide information about the current trends in the treatment of OLP across Europe.
Materials And Methods: Data and histopathological records of patients with OLP were retrospectives revised and only those patients that fulfilled the diagnostic criteria from the 2016 position paper by American Academy of Oral and Maxillofacial Pathology were included.
The oncogenic potential of salivary microRNA-93 and microRNA-412-3p in oral lichen planus: a case-control study.
BDJ Open
December 2024
Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Background: Oral Lichen Planus is one of the most popular chronic mucocutaneous diseases. It is classified as potentially malignant lesions. Many microRNAs can be used as biological markers for the disease and for its malignant transformation.
View Article and Find Full Text PDFRapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing.
Allergol Select
October 2024
Center for Child and Adolescent Health, Helios Hospital Krefeld, Academic Hospital of RWTH Aachen, Krefeld.
Article Synopsis
- Primary atopic disorders (PAD) are rare genetic conditions caused by specific gene variants that affect skin and immune function, making diagnosis challenging among common allergic disease cases.
- Identifying PAD requires recognizing clinical red flags like family history and unusual infections, as conventional lab tests are inadequate for definitive diagnosis.
- Whole-genome sequencing (WGS) enhances diagnostic efficiency and accuracy, but requires careful interpretation and collaboration among specialists to effectively manage PAD cases.
A Tissue-Engineered Model of T-Cell-Mediated Oral Mucosal Inflammatory Disease.
J Invest Dermatol
October 2024
School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom; Insigneo Institute, University of Sheffield, Sheffield, United Kingdom.
Article Synopsis
- Scientists developed a tissue-engineered model of oral mucosa to study oral lichen planus (OLP) and its inflammatory properties, addressing the lack of experimental models for this condition.
- They used activated T-cells to simulate OLP pathogenesis, resulting in increased secretion of inflammatory substances and tissue damage, which was assessed through histological analysis.
- The study tested treatment options such as JAK inhibitors and clobetasol, showing potential for these methods to reduce cytokine release and prevent tissue damage, paving the way for future therapeutic research.
Clinical and Biological Perspectives on Noncanonical Esophageal Squamous Cell Carcinoma in Rare Subtypes.
Am J Gastroenterol
December 2024
Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA.
Article Synopsis
- Esophageal squamous cell carcinoma (ESCC) is primarily caused by environmental factors like alcohol and tobacco, but it can also arise from rare non-environmental conditions that are often overlooked.
- The review emphasizes the necessity for healthcare professionals to recognize these rare diseases (like Fanconi anemia and achalasia) as high-risk for developing ESCC, advocating for early detection through endoscopic evaluation and advanced imaging techniques.
- It highlights common underlying mechanisms of malignant transformation in these conditions, such as abnormal cell growth, inflammation, and genetic instability, to improve understanding and screening strategies for ESCC.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!