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Osteology and functional morphology of a transitional pterosaur Dearc sgiathanach from the Middle Jurassic (Bathonian) of Scotland.
BMC Ecol Evol
January 2025
School of GeoSciences, University of Edinburgh, Edinburgh, Scotland.
Pterosaurs were the first vertebrates to evolve active flight. The lack of many well-preserved pterosaur fossils limits our understanding of the functional anatomy and behavior of these flight pioneers, particularly from their early history (Triassic to Middle Jurassic). Here we describe in detail the osteology of an exceptionally preserved Middle Jurassic pterosaur, the holotype of Dearc sgiathanach from the Isle of Skye, Scotland.
View Article and Find Full Text PDFBiomechanical analysis of step-up and step-down tasks in knee osteoarthritis: Insights from leading and trailing limbs.
Clin Biomech (Bristol)
January 2025
Rehabilitation Research Institute of Singapore, Nanyang Technological University, 11 Mandalay Rd, #14-03 Clinical Sciences Building, 308232, Singapore; Department of Orthopaedic Surgery, Woodlands Health, National Healthcare Group, 737628, Singapore.
Background: Stair climbing tests are pivotal when assessing physical performance in knee osteoarthritis patients, yet the biomechanical strategies that underpin poor stair climbing ability are heterogeneously reported. Single step tasks emulate a step-by-step gait pattern, an approach associated with knee pain when stair climbing. The objective of this study is to analyse the biomechanics and electromyography activity of both the leading and trailing limbs during single Step-up and Down tasks in knee osteoarthritis patients.
View Article and Find Full Text PDFEye Movements and the Intraorbital Subarachnoid Space: Potential Contribution of Altered Cerebrospinal Fluid Pumping in Optic Neuropathies.
Invest Ophthalmol Vis Sci
January 2025
Department of Ophthalmology, University of California, Los Angeles, California, United States.
Purpose: The optic nerve (ON) is mechanically perturbed by eye movements that shift cerebrospinal fluid (CSF) within its surrounding dural sheath. This study compared changes in ON length and CSF volume within the intraorbital ON sheath caused by eye movements in healthy subjects and patients with optic neuropathies.
Methods: Twenty-one healthy controls were compared with 11 patients having primary open angle glaucoma (POAG) at normal intraocular pressure (IOP), and 11 with chronic non-arteritic anterior ischemic optic neuropathy (NA-AION).
Handlebar Width Choices Must Be Considered for Female Cyclists.
J Funct Morphol Kinesiol
January 2025
Office Physical Education, National Pingtung University of Science and Technology, Pingtung 912301, Taiwan.
: The effects of handlebar width on female cyclists are understudied; therefore, it is necessary to find an optimal handlebar width for women based on anatomical features. : Ten healthy women participants whose muscle activity and movements were measured using four kinds of handlebar widths were observed using EMG and 3D motion analysis systems. Participants cycled at a constant cadence and power output using different handlebar widths in a counterbalanced order.
View Article and Find Full Text PDFThe Issue of "Smart Drugs" on the Example of Modafinil: Toxicological Analysis of Evidences and Biological Samples.
J Xenobiot
January 2025
Department of Social Sciences and Infectious Diseases, Faculty of Medicine, Wroclaw University of Science and Technology, 27 Wybrzeze Wyspianskiego Street, 50370 Wroclaw, Poland.
Cognitive enhancement through stimulants such as modafinil is becoming increasingly popular, with many individuals using prescription stimulants for non-medical purposes to improve alertness, attention, and mood. The misuse of such substances has raised concerns, particularly in forensic toxicology. The UHPLC-QqQ-MS/MS method was developed to quantify modafinil in evidentiary samples and biological materials.
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