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Advances in RNA editing in hematopoiesis and associated malignancies.
Blood
January 2025
State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College; Center for Stem Cell Medicine,, Tianjin, China.
Adenosine-to-inosine (A-to-I) RNA editing is a prevalent RNA modification essential for cell survival. The process is catalyzed by the Adenosine Deaminase Acting on RNA (ADAR) enzyme family that converts adenosines in double-stranded RNAs (dsRNAs) into inosines, which are read as guanosines during translation. Deep sequencing has helped to reveal that A-to-I editing occurs across various types of RNAs to affect their functions.
View Article and Find Full Text PDFModel minority stereotype stress and depressive symptoms among Asian American science, technology, engineering, and mathematics students: The mediating role of rumination.
J Couns Psychol
January 2025
Department of Psychology, University of Hawaii at Hilo.
The model minority stereotype (MMS) is deeply embedded within the society of the United States, including in the science, technology, engineering, and mathematics (STEM) fields. This has resulted in the neglect of STEM Asian American students' psychological needs by researchers and service providers while simultaneously pressuring the students to pursue unattainable goals. The aim of the present study was to explore the mechanism of how stress from the MMS might be related to depressive symptoms.
View Article and Find Full Text PDFA single-cell atlas of the Culex tarsalis midgut during West Nile virus infection.
PLoS Pathog
January 2025
Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
The mosquito midgut functions as a key interface between pathogen and vector. However, studies of midgut physiology and virus infection dynamics are scarce, and in Culex tarsalis-an extremely efficient vector of West Nile virus (WNV)-nonexistent. We performed single-cell RNA sequencing on Cx.
View Article and Find Full Text PDFExploring the landscape of exosomes in heart failure: a bibliometric analysis.
Int J Surg
January 2025
Department of Colorectal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Background: Exosomes, which carry bioactive RNAs, proteins, lipids, and metabolites, have emerged as novel diagnostic markers and therapeutic agents for heart failure (HF). This study aims to elucidate the trends, key contributors, and research hotspots of exosomes in HF.
Methods: We collected publications related to exosomes in HF from the Web of Science Core Collection.
Correction: Engineering extracellular vesicles for ROS scavenging and tissue regeneration.
Nano Converg
January 2025
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21205, USA.
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