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Creation of nomograms that combine clinical, CT, and radiographic features to separate benign from malignant diseases using spiculation or (and) lobulation signs.
Curr Probl Diagn Radiol
December 2024
Chief Physician, No.215 Heping West Road, Second Hospital of Hebei Medical University, Xinhua District, Hebei Province China. Electronic address:
Background: Distinguishing between benign and malignant pulmonary nodules based on CT imaging features such as the spiculation sign and/or lobulation sign remains challenging and these nodules are often misinterpreted as malignant tumors. this retrospective study aimed to develop a prediction model to estimate the likelihood of benign and malignant lung nodules exhibiting spiculation and/or lobulation signs.
Methods: A total of 500 patients with pulmonary nodules from June 2022 to August 2024 were retrospectively analyzed.
Role of narrow band imaging in assessing bronchial mucosal hypervascularization in COVID-19 patients.
Respir Med Res
January 2025
Pneumology Department, University Hospital Centre Amiens-Picardie, Amiens, France; AGIR Unit, University Picardie Jules Vernes, Amiens, France.
Background: SARS-CoV-2 virus which targets the lung vasculature is supposed to affect both pulmonary and bronchial arteries. This study evaluated the tracheobronchial vascularization density observed with narrow band imaging (NBI) in patients hospitalized for COVID-19 pneumonia. To determine if the observed changes were specific of COVID-19 patients, the procedure was also performed in non-COVID-19 patients.
View Article and Find Full Text PDFAnti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer.
Pathol Oncol Res
January 2025
Department of Pulmonology, Semmelweis University, Budapest, Hungary.
Objectives: Spingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circulating S1P and anti-ceramide antibody as biomarkers in non-small cell lung cancer (NSCLC).
View Article and Find Full Text PDFComparative thoracic radiography in healthy and tuberculosis-positive sun bears ().
Front Vet Sci
January 2025
School of Veterinary Medicine, Murdoch University, Perth, WA, Australia.
Early and accurate diagnosis of pulmonary tuberculosis (TB) is key to effective outbreak management, and in humans thoracic radiography is used extensively for screening purposes. In wildlife TB radiography is a relatively accessible diagnostic tool, particularly in under-resourced settings, however its use is limited by body size. Sun bears are susceptible to human-associated TB, and their small body size makes thoracic radiography feasible.
View Article and Find Full Text PDFDiagnostic Value of Endobronchial Ultrasound-Guided Intranodal Forceps Biopsies Combined with Rapid On-Site Evaluation for Mediastinal/Hilar Lymph Node Disease.
Br J Hosp Med (Lond)
December 2024
Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the standard method for sampling mediastinal/hilar lymph node disease. However, the smaller samples obtained via needle aspiration have a lower diagnostic rate for benign compared to malignant diseases. The low diagnostic rates have been reported to be improved through using endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB), but the implementation of IFB presents technical challenges, as described with variable results in certain studies.
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