Applications of the oral scraped (exfoliative) cytology in oral cancer and precancer.

Med Oral Patol Oral Cir Bucal

Medicina Bucal, Unidad de Patología Oral y Maxilofacial, Departamento de Estomatología, Universidad del País Vasco EHU, Leioa, Vizcaya, Spain.

Published: January 2006

AI Article Synopsis

  • Scraped (exfoliative) cytology is a non-invasive procedure that has become more relevant in diagnosing and monitoring oral precancerous and cancerous conditions.
  • New techniques like "brush biopsy" and advanced molecular studies have enhanced the validity and applications of this method in understanding oral pathology.
  • The review aims to explore the latest developments in scraped cytology, particularly its molecular aspects and their significance for diagnosis and prognosis.

Article Abstract

Scraped (exfoliative) cytology is a simple and harmless procedure, which has been a controversial technique according to its real validity in oral pathology. Lately it has re-emerged due to its application in oral precancer and cancer as a diagnostic and predictive method as well as for monitoring patients. New diagnostic techniques have been developed, such as "brush biopsy" and multiple molecular studies using the cells collected. In this review we are going to analyse the more novel aspects related with the applications of the scraped or exfoliative cytology in oral precancerous and cancerous pathology, specially focusing on molecular studies and their diagnostic and prognostic implications.

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