The relationship of neuropsychological measures of frontal lobe function to age differences in false recall was assessed using the Deese/Roediger-McDermott associative false memory paradigm (Deese, 1959; Roediger & McDermott, 1995). As other studies have found, older adults were less likely to correctly recall studied items and more likely to falsely recall highly related but nonpresented items than were younger adults. When older adults were divided based on a composite measure of frontal lobe functioning, this age difference was found only for low frontal lobe functioning individuals. High frontal lobe functioning older adults and young adults had equivalent levels of false recall, as well as equivalent levels of veridical recall. These results suggest that age differences in memory may be due to declines in frontal lobe function. More important, our findings indicate that declines in veridical recall and increases in false recall are not an inevitable consequence of aging.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.3758/bf03196722 | DOI Listing |
Biomedicines
November 2024
Cancer Epidemiology and Cancer Services Research, Centre for Cancer, Society & Public Health, Bermondsey Wing, King's College London, 3rd Floor, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.
Molecular profiles can predict which patients will respond to current standard treatment and new targeted therapy regimens. Using data from a highly diverse population of approximately three million in Southeast London and Kent, this study aims to evaluate the prevalence of IDH1 mutation and MGMT promoter methylation in the gliomas diagnosed in adult patients and to explore correlations with patients' demographic and clinicopathological characteristics. Anonymised data on 749 adult patients diagnosed with a glioma in 2015-2019 at King's College Hospital were extracted.
View Article and Find Full Text PDFGenes (Basel)
December 2024
Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA.
Background: (absent, small, or homeotic-like 1), a histone methyltransferase, has been identified as a high-risk gene for autism spectrum disorder (ASD). We previously showed that postnatal severe deficiency in the prefrontal cortex (PFC) of male and female mice caused seizures. However, the synaptic mechanisms underlying autism-like social deficits and seizures need to be elucidated.
View Article and Find Full Text PDFBiomolecules
December 2024
Division of Experimental and Molecular Psychiatry, Department of Psychiatry, Psychotherapy and Preventive Medicine, LWL University Hospital, Ruhr University Bochum, 44801 Bochum, Germany.
Exposure to stress during early and late childhood can lead to long-lasting neurobiological and behavioral impairments. Although sensitive periods for stress exposure are well established, less is known about the trajectory of induced alterations throughout development. In this study, we investigated the impact of maternal separation (MS), social isolation, and their combination on anxiety-like behavior and gene expression across developmental stages.
View Article and Find Full Text PDFSci Rep
January 2025
Women's Operational Military Exposure Network Center of Excellence (WOMEN COE), VA Palo Alto Health Care System, Palo Alto, USA.
Anhedonia, a core symptom of depression, has been defined as the loss of pleasure or lack of reactivity to pleasurable stimuli. Considering the relevance of alpha asymmetry to MDD and anhedonia, we explored the effect of dorsolateral prefrontal cortex (DLPFC) stimulation on frontal and posterior EEG alpha asymmetry (FAA and PAA, respectively), in this exploratory investigation. 61 participants randomly received sham (n = 11), bilateral (BS; n = 25), or unilateral stimulation (US; n = 25) of the DLPFC.
View Article and Find Full Text PDFNat Commun
January 2025
Center for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology, Suita, Japan.
The ability to estimate numerical magnitude is essential for decision-making and is thought to underlie arithmetic skills. In humans, neural populations in the frontoparietal regions are tuned to represent numerosity. However, it remains unclear whether their response properties are fixed to a specific numerosity (i.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!