AI Article Synopsis
- Acrylic compounds are increasingly used in various industries and hobbies but can cause skin and respiratory issues, including bronchial asthma.
- A case study of a 32-year-old female worker used ethyl cyanoacrylate daily and developed occupational asthma after experiencing symptoms like dry cough and shortness of breath.
- The diagnosis was confirmed through a bronchial challenge test, highlighting the need for this method as the primary diagnostic tool for asthma linked to acrylate exposure, as traditional tests are not effective.
Article Abstract
Background: An increased use of acrylic compounds is observed in different industries, home repairs and hobbies. These compounds are known to cause skin sensitisation, irritation of mucous membranes and bronchial asthma. Methyl cyanoacrylate is moderately likely to be a sensitizer, while ethyl cyanoacrylate might be a weak sensitizer.
Objectives: Clinical evaluation of a case of occupational asthma due to cyanoacrylate.
Methods: A female worker, aged 32 years, used ethyl cyanoacrylate daily. After 2 months she experienced dry cough and shortness breath. Some weeks later she developed bronchial asthma. The diagnosis of occupational asthma was based on the work-related symptoms and the inhalation challenge test result.
Results: A late asthmatic response was observed with a maximum fall in FEV1 of 26% 345 minutes after exposure. Complete clinical and functional recovery was observed after inhalation of a broncho-dilating agent.
Conclusions: Acrylates are new occupational sensitising agents, causing rhinitis and asthma. It is not possible to perform prick tests or specific IgE measurements for these compounds. The bronchial challenge test is therefore the sole valid test for the diagnosis of occupational asthma.
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