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Antimicrobial susceptibility of Shigella sonnei isolates in Japan and molecular analysis of S. sonnei isolates with reduced susceptibility to fluoroquinolones. | LitMetric

AI Article Synopsis

  • The study tested Shigella sonnei isolates from both imported and domestic infections in Japan during 2001 and 2002.
  • Some isolates displayed resistance to drugs like nalidixic acid, tetracycline, and trimethoprim-sulfamethoxazole.
  • While many nalidixic acid-resistant strains had reduced susceptibility to fluoroquinolones, they did not exhibit full resistance to these medications.

Article Abstract

We performed susceptibility testing with Shigella sonnei isolates from imported and domestic cases of infection in Japan during 2001 and 2002. Some S. sonnei isolates were resistant to nalidixic acid, tetracycline, and trimethoprim-sulfamethoxazole. Most of the nalidixic acid-resistant strains showed reduced susceptibility to fluoroquinolones but did not show fluoroquinolone resistance.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549262PMC
http://dx.doi.org/10.1128/AAC.49.3.1203-1205.2005DOI Listing

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