AI Article Synopsis
- Children with fetal alcohol spectrum disorder (FASD) are frequently diagnosed with ADHD, exhibiting increased reaction time variability and false alarms in tasks.
- A study using adult rats exposed to ethanol during pregnancy demonstrated that these rats also had variable reaction time distributions and increased false alarms in a choice reaction time task.
- The findings suggest that both prenatal ethanol exposure in rats and FASD in children lead to similar attention deficits.
Article Abstract
Children with fetal alcohol spectrum disorder (FASD) are often diagnosed with attention-deficit/ hyperactivity disorder (ADHD). These children show increases in reaction time (RT) variability and false alarms on choice reaction time (CRT) tasks. In this study, adult rats prenatally exposed to ethanol were trained to perform a CRT task. An analysis of the distribution of RTs obtained from the CRT task found that rats with a history of prenatal ethanol exposure had more variable RT distributions, possibly because of lapses of attention. In addition, it was found that, similar to children with FASD, the ethanol-exposed rats had more false alarms. Thus, rats with prenatal ethanol exposure show attention deficits that are similar to those of children with FASD and ADHD.
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| http://dx.doi.org/10.1037/0735-7044.119.1.302 | DOI Listing |
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