[Lymphocyte subpopulation changes in children with chronic virus hepatitis D and B].

We observed 367 children with chronic viral hepatitis Delta (CVHD) and B (CVHB) and found strict secondary T-immunodeficiency, more expressed in children with CVHD. We have found also the most characterizing changes of lymphocytes subpopulation and natural killer-cells depending on etiology of CVH. As for CVHD it is characterized by more significant decrease in CD4-lymphocytes, as for CVHB--CD8-lymphocytes. The above mentioned changes of lymphocytes subpopulation in patients with CVHD and CVHB show different pathological mechanisms of these two diseases, that should be taken into account treating such patients.