[Study on the chemical constituents from Picria fel-tarrae].

Zhongguo Zhong Yao Za Zhi

Institute of Chinese Medica, Beijing University of Traditional Chinese Medicine, Beijing 100102, China.

Published: February 2004

Objective: To isolate and identify compounds from Picria fel-tarrae in order to utilize it better.

Method: Constituents from Picria fel-tarrae were isolated by several column chromatography and their structures were elucidated on the basis of chemical and spectral analysis.

Result: Six compounds, N-benzoylphenylalanyl-L-phenylalaninol acetate (1), 1-hydroxy-7-hydroxymethyl-9,10-anthraquinone (2), 9, 16-dioxo-10,12,14-octadeca-trienoic acid (3), 5,7,4'-trihydroxy-flavone (4), beta-sitosterol (5), and daucosterol (6) were obtained from the fraction with relatively low polarity of EtOH extract of Picria fel-tarrae.

Conclusion: Compounds 1-6 were isolated from picria fel-tarrae Lour for the first time, and the 13C-NMR data of compounds 1-3 are provided firstly in the literature.

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