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Continuous reference intervals for plasma cystatin C and creatinine in Vietnamese children.
EJIFCC
December 2024
Department of Laboratory Medicine, National University Hospital, Singapore.
Background: Serum (plasma) creatinine and cystatin C are widely used in pediatric clinical practice to assess glomerular filtration rate. Both markers have limitations due to the low index of individuality, which affects the clinical sensitivity of population-based reference intervals, especially when wide age ranges are considered. This study aimed to establish age-related reference intervals for plasma cystatin C and creatinine in Vietnamese children.
View Article and Find Full Text PDFCorrelation between Occupational Noise Exposure and Renal Dysfunction in Male Workers.
Noise Health
January 2025
Department of Pain, Qingdao Municipal Hospital, Qingdao, China.
Objective: This study aimed to explore the relationship between occupational noise exposure and renal dysfunction in male workers.
Methods: A total of 160 male workers (the number of people who met the inclusion criteria) who underwent health examinations in Qingdao Municipal Hospital from January 2023 to December 2023 were grouped into a noise group (80 cases) and a control group (80 cases) based on whether they engaged in noise work. We compared the differences in creatinine (CREA), cystatin C (CysC) and blood urea nitrogen (BUN) levels between the two groups.
[Construction of prognostic prediction model for patients with sepsis-induced acute kidney injury treated with continuous renal replacement therapy].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
December 2024
Department of Urology, Fuyang People's Hospital, Fuyang 236000, Anhui, China. Corresponding author: Li Dongfeng, Email:
Objective: To explore the influencing factors of prognosis in patients with sepsis-induced acute kidney injury undergoing continuous renal replacement therapy (CRRT), and to construct a mortality risk prediction model.
Methods: A retrospective research method was adopted, patients with sepsis-induced acute kidney injury who received CRRT at Fuyang People's Hospital from February 2021 to September 2023 were included in this study. Collect general information, comorbidities, vital signs, laboratory indicators, disease severity scores, treatment status, length of stay in the intensive care unit (ICU), and 28-day prognosis were collected within 24 hours of patient enrollment.
Expression and clinical significance of 25-hydroxyvitamin D, insulin-like growth factor 1, and beta-2 microglobulin in cognitive dysfunction after ischemic stroke in the elderly.
Neuroreport
January 2025
Department of Neurology, the Second Affiliated Hospital of Guizhou Medical University, Kaili, Guizhou Province, China.
Article Synopsis
- The study examined the relationship between serum levels of 25-hydroxyvitamin D, IGF-1, and beta-2 microglobulin in elderly patients with cognitive dysfunction after ischemic stroke.
- Data from 160 geriatric patients were analyzed, revealing that lower levels of 25-OH-VD and IGF-1 were linked to worse cognitive scores, while higher β2-MG levels correlated with greater cognitive decline.
- Factors such as diabetes, low education levels, age, and certain serum markers were identified as independent risk factors for developing cognitive dysfunction post-stroke, suggesting the importance of monitoring these serum levels in clinical settings.
Predictive value of creatinine-cystatin C ratio for mortality and technique failure in anuric peritoneal dialysis patients.
Ren Fail
December 2025
National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu, China.
Objectives: Both serum creatinine and cystatin C serve as dependable markers of renal function and have demonstrated a correlation with clinical outcomes in diverse conditions, particularly through the ratio of creatinine to cystatin C (Cr/CysC). Anuric patients undergoing peritoneal dialysis (PD) depend entirely on the clearance of peritoneal solutes. This research posits that the Cr/CysC ratio may predict all-cause mortality and technique failure in anuric PD patients.
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