This study aimed to determine the clinical epidemiological profile of the snake bites attended at the reference hospital of Acre. One hundred-forty four patients were studied prospectively, from January to December 2002. One hundred-thirteen (78.5%) cases were classified as accidents by venomous snakes. The genera Bothrops, Lachesis and Micrurus were responsible, respectively, for 75.7%, 2.1% e 0.7% cases. The accidents predominated in males (78.5%), rural workers (51.4%) and between 10 and 29 years old (43.8%). The distribution according to the severity of poisoning by genera Bothrops was: moderate (48.6%), mild (31.2%) or severe (20.2%). Two cases of Bothrops accident did not receive serum therapy. However, the antivenom was administered in twenty-three patients without envenoming. In conclusion, the results obtained were different of the observed by another authors with respect to the severity of accidents and suitable treatment.
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http://dx.doi.org/10.1590/s0037-86822005000100004 | DOI Listing |
Comp Biochem Physiol C Toxicol Pharmacol
January 2025
Laboratory of Herpetology, Instituto Butantan, São Paulo 05503-900, SP, Brazil; Interunidades em Biotecnologia, Instituto de Ciências Biomédicas-Instituto de Pesquisas Tecnológicas-Instituto Butantan, Universidade de São Paulo, São Paulo 05508-900, SP, Brazil. Electronic address:
One of the main clinical manifestations presented by victims of snake bite envenoming are coagulation disorders. Considering that fibrinogen is a key molecule for crosslinked fibrin clot formation, the objective of this work was the quantitative analysis of the fibrinogenolytic activity of snakes of medical importance in Brazil and neutralization by specific antivenom. For this, pools of three genera of medical importance (Bothrops, Crotalus and Lachesis) that are used for the production of antivenom were used, and three pools of species of the genus Bothrops that are not part of the pool for the production of antivenom.
View Article and Find Full Text PDFToxicon
October 2024
Centro de Informação e Assistência Toxicológica de Campinas (CIATox-Campinas), Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Cidade Universitária Zeferino Vaz, Rua Vital Brazil 80, Campinas, 13083-888, SP, Brazil; Departamento de Medicina Translacional (Área de Farmacologia), Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Cidade Universitária Zeferino Vaz, Rua Vital Brazil 80, Campinas, 13083-888, SP, Brazil.
Despite the wide range of institutions that maintain venomous snakes in captivity in Brazil there are no comprehensive data on the occurrence of snakebites and envenomations in these places. We examined the range of native and exotic species of venomous snakes kept by Brazilian zoos and serpentaria (scientific and commercial) and assessed the frequency of snakebites in workers handling these snakes during a 10-year period (2012-2021). Twenty-two (73.
View Article and Find Full Text PDFVet Parasitol Reg Stud Reports
August 2024
Laboratório de Patologia Animal, Instituto da Saúde e Produção Animal (ISPA), Universidade Federal Rural da Amazônia (UFRA). Caixa postal, 917, CEP 66.077-530 Belém, Pará, Brazil.
Snakes of the genus Bothrops inhabit tropical forests in Central and South America and are important for the biomedical and pharmaceutical industries because of the chemical properties of their venom. They serve as either definitive or intermediate hosts for many parasitic helminths. The Marajó Island (Brazil) is the natural habitat of venomous snakes, Bothrops atrox and Bothrops marajoensis, which are often found around rural and peri-urban areas and are known to bite humans.
View Article and Find Full Text PDFPurinergic Signal
July 2024
Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Laboratório de Biologia Molecular e Culturas Celulares, Universidade Federal de Mato Grosso do Sul (UFMS), Av. Costa e Silva, s/n. Bairro Universitário, Campo Grande, MS, CEP: 79070-900, Brazil.
Snake bites are a severe problem in the countryside of Brazil and are usually attributed to snakes of the genera Bothrops, Crotalus, and Lachesis. Snake venom can release ectoenzymes and nucleotidases that modulate the purinergic system. In addition to serum therapy against snake poisoning, medicinal plants with anti-inflammatory activities, such as Tabebuia aurea, is empirically applied in accidents that occur in difficult-to-access areas.
View Article and Find Full Text PDFHeliyon
March 2024
Universidad Icesi, Facultad de Ciencias de la Salud, Cali, Colombia.
Background: Snake envenomation is a medical condition with high morbidity and mortality in southwestern Colombia.
Objectives: To describe the characteristics of the envenomation caused by Viperidae snakes view in a highly complex hospital in Southwestern Colombia.
Methods: A cross-sectional study was carried out.
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