There are few written documents and even fewer accurate data on the public hygiene of Székelykeresztúr (today also, as Cristuru Secuesc in Rumania), at the remote southern parts of historic Hungary. Ethno-medicine was certainly based on oral traditions, and its observations, experience and practice included the widespread use of magic and quackmedicine. The repeated epidemics of plague, cholera and diphteria - some even occurring in the 20th c. - forced local authorities to introduce counter-measures. The number of university trained, qualified physicians remained, however, inadequate during mid 19th c. in Transylvania: in 1843, there were only 69 of them and though it was levelled up to 94 by 1863, but even this increase was less than enough. Despite the devoted efforts of the qualified medical staff, medical care in this under-urbanised and generally underdeveloped region remained weak. Modern scientific medicine only came the 20th c. and set only slowly through, so that in the first decades of the 20th c. the yearly increase of the Székely (Szekler) population was between 0 and 4.9%. The centuries old backwardness of the region, was only slowly overcome.
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Australas J Dermatol
January 2025
The Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Background: Recent Australian trends indicate that shave biopsies for diagnosing lesions suspicious of melanoma are increasing, yet reasons for this remain relatively unknown. We sought to understand which factors influence Australian clinicians' use of shave biopsy for managing thin lesions suspicious of melanoma in sites of low cosmetic sensitivity.
Methods: We used a convergent, exploratory mixed-methods design, with a cross-sectional online survey (n = 59) and semi-structured qualitative interviews (n = 15).
BMC Genomics
January 2025
Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, L7 8TX, UK.
Age-related muscle wasting, sarcopenia is an extensive loss of muscle mass and strength with age and a major cause of disability and accidents in the elderly. Mechanisms purported to be involved in muscle ageing and sarcopenia are numerous but poorly understood, necessitating deeper study. Hence, we employed high-throughput RNA sequencing to survey the global changes in protein-coding gene expression occurring in skeletal muscle with age.
View Article and Find Full Text PDFBMC Med
January 2025
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Background: Since older adults spend significant time in their neighborhood environment, environmental factors such as neighborhood socioeconomic disadvantage, high racial segregation, low healthy food availability, low access to recreation, and minimal social engagement may have adverse effects on cognitive function and increase susceptibility to dementia. DNA methylation, which is associated with neighborhood characteristics as well as cognitive function and white matter hyperintensity (WMH), may act as a mediator between neighborhood characteristics and neurocognitive outcomes.
Methods: In this study, we examined whether DNA methylation in peripheral blood leukocytes mediates the relationship between neighborhood characteristics and cognitive function (N = 542) or WMH (N = 466) in older African American (AA) participants without preliminary evidence of dementia from the Genetic Epidemiology Network of Arteriopathy (GENOA).
Acad Radiol
January 2025
College of Medicine and Surgery, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia (D.H.A., D.S.A, D.S.AlH., F.N.A., R.H.A., N.T.S.). Electronic address:
Rationale And Objectives: Radiology plays a crucial role in modern healthcare as it facilitates the diagnosis and treatment of various medical conditions in different specialties. Therefore, this study aimed to gain insights into the factors that contribute to medical students choosing radiology as a future career.
Materials And Methods: This cross-sectional study used an online, self-administered questionnaire.
J Oral Facial Pain Headache
September 2024
Department of Dentistry, School of Health Sciences, University of Brasília (UnB), 70910-900 Brasília, DF, Brazil.
Temporomandibular disorders (TMD) usually affect the stomatognathic system and can be symptomatic. Patients often self-medicate to relieve symptoms, and this can increase the risk of complications such as adverse drug reactions, overdose, physical and psychological dependence, and delay of appropriate treatment. It is important for dentists to know the prevalence of self-medication to investigate this condition in their patients, thus the primary aim of this study was to estimate the prevalence of self-medication among university students with no TMD, non-painful TMD and painful TMD and the secondary aim was to assess association with independent factors.
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