Acute or subacute bipallidal lesion, an uncommon radiological feature produced by metabolic disorders or poisoning, has never been attributed to ethylene glycol (EG) intoxication. This 50-year-old Afro-Caribbean alcoholic man had unexplained loss of consciousness. Blood tests showed osmolar gap. Drug screening was positive for EG at 6.06 mmol/l. Brain CT revealed bilateral pallidal haemorrhage. Pallidal haematoma, which could be related to deposition of oxalate crystals issued from EG metabolism, should lead to toxicological screening.
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http://dx.doi.org/10.1007/s00234-005-1347-y | DOI Listing |
J Org Chem
January 2025
Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan.
Arynes are important synthetic intermediates that are usually generated under alkaline conditions. We developed a method for generating arynes using two hydroxy compounds as activators. -Triazenylarylboronic acids generate (hetero)arynes when activated by a combination of ethylene glycol, pinacol, and -nitrophenol; these arynes then react with a range of arynophiles under slightly acidic conditions that complement the conventional basic conditions with unique chemoselectivities observed even in the presence of excess hydroxy compounds.
View Article and Find Full Text PDFRSC Adv
January 2025
Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology (KAIST) 291 Daehak-ro, Yuseong-gu Daejeon 34141 Republic of Korea
Zircaloy-4 (Zr-4) is widely used as the cladding material in nuclear power plants (NPPs) due to its excellent corrosion resistance and low neutron absorption cross-section. Under Loss of Coolant Accident (LOCA) conditions, oxidation of Zr-4 can compromise the safety of the NPPs by accelerating hydrogen production. Therefore, enhancing the oxidation resistance of Zr-4 is a critical research focus.
View Article and Find Full Text PDFMikrochim Acta
January 2025
Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani, 34190, Thailand.
Carcinoembryonic antigen (CEA) and C-reactive protein (CRP) are biomacromolecules known as cancer and inflammatory markers. Thus, they play a crucial role in early cancer diagnosis, post-treatment recurrence detection, and tumor risk assessment. This paper describes the development of an ultrasensitive and selective imprinted paper-based analytical device (PAD) as impedance sensor for determination of CEA and CRP in serum samples for point-of-care testing (POCT).
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
State Key Laboratory of Organic-Inorganic Composites, College of Life Science and Technology, Beijing University of Chemical Technology, No. 15 East Road of North Third Ring Road, Chao Yang District, Beijing 100029, China. Electronic address:
A comprehensive study was conducted to determine the effects of water and ethylene glycol (EG) on biomass pretreatment using a binary deep eutectic solvent (DES) containing choline chloride and acetic acid (1ChCl3AC) at a mole ratio of 1:3. Different quantities of water and EG were combined with 1ChCl3AC to pretreat wheat straw, miscanthus, eucalyptus, and sorghum stalk at 130 °C for 6 h. The changes in nanopore structure and surface roughness of wet biomass, as well as biomass crystallinity after 1ChCl3AC-based pretreatment were investigated using XRD and small-angle neutron scattering (SANS).
View Article and Find Full Text PDFJ Chem Theory Comput
January 2025
Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560-8531, Japan.
Solvent environment may significantly affect the equilibria involving flexible solute species, such as proteins and polymers. In the present work, a computation scheme is formulated for the change in the excess chemical potential of a flexible solute molecule upon variation of the solvent condition. The formulation adopts the scheme of error minimization in parallel to the method of Bennett acceptance ratio, and an exact expression is presented that provides the change in the excess chemical potential from solvation free energies computed in two solvent conditions of interest.
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