AI Article Synopsis
- Growth arrest from physeal bridge formation is a rare but known complication that can lead to growth issues in children after bone injuries.
- Resection of the physeal bridge, along with interposition materials, is an effective treatment for preventing or correcting growth deformities when there's still significant growth potential.
- Current research is exploring gene therapy and the use of cartilage or cultured chondrocytes to enhance treatment outcomes for growth arrest.
Article Abstract
Growth arrest secondary to physeal bridge formation is an uncommon but well-recognized complication of physeal fractures and other injuries. Regardless of the underlying etiology, physeal bridges may cause angular and/or longitudinal growth disturbances, with progression dependent on the remaining physeal growth potential. Physeal bridge resection and insertion of interposition material releases the tethering effect of the bridge. Physeal bridge resection has become an accepted treatment option for patients with existing or developing deformity and for those with at least 2 years or 2 cm of growth remaining. Current experimental research is focused on the use of gene therapy and other factors that enhance chondrocyte proliferation to improve the management of growth arrest. The use of cartilage and cultured chondrocytes as interposition material after physeal bridge resection is an area of active research.
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| http://dx.doi.org/10.5435/00124635-200501000-00007 | DOI Listing |
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