The aim was to estimate the adult exposure to cadmium, lead and mercury from daily household diets in Eastern Poland (Lublin city and province). A duplicate diet approach was used to top collect diet samples in 1990, 1993, 1998 and 2002. Cadmium and lead contents were measured by flame atomic absorption and the mercury content was measured by cold vapour atomic absorption spectrometry. The intake of the three elements was calculated using FOOD computer software. The exposure to cadmium taken with daily diets was from 16.4-34.5 microg/person/day (27-58% PTWI). The lead exposure was 66.5-106 microg/person/day (31-49% PTWI), which posed a smaller risk, and the exposure risk to mercury of 4.08-6.65 microg/person/day (10-16% PTWI) was even lower.
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http://dx.doi.org/10.1080/02652030400004218 | DOI Listing |
FASEB J
January 2025
Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Fetal growth restriction (FGR) is characterized by the inability of the fetus to achieve its growth potential due to pathological factors, most commonly impaired placental trophoblast cell function. Currently, effective prevention and treatment methods of FGR are limited. We aimed to explore the pathogenesis of FGR and provide potential strategies for mitigating its occurrence.
View Article and Find Full Text PDFSci Rep
January 2025
School of Public Health, Chongqing Medical University, Chongqing, China.
Cumulative risk assessment is significant for evaluating the combined exposure to multiple substances, but its widespread acceptance and application have been limited due to the complexity of clarifying and assessing actual exposure. In this study, we conducted a cumulative risk assessment based on hazard-driven criteria to evaluate the co-exposure to elemental contaminants in the diet of the population in Chongqing Municipality. The cumulative risk was calculated and evaluated using Monte Carlo modeling and the modified Reference Point Index (mRPI) method.
View Article and Find Full Text PDFHum Mol Genet
January 2025
Epidemiology Program, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, HI 96813, United States.
Background: Cadmium (Cd), classified as an International Agency for Research on Cancer (IARC) Group 1 human carcinogen, is present in cigarette smoke. Recent studies have illustrated the potential role of genetics in influencing Cd biomarker levels.
Methods: We conducted a genome-wide association study (GWAS) of urinary Cd levels in 1977 current smokers from the Multiethnic Cohort Study, comprising participants from five different racial and ethnic groups.
Environ Health
January 2025
Department of Family Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
DNA methylation is a critical step in brain development, 5-Methyl-2'-deoxycytidine (5mdC) is one of the global DNA methylation markers. Arsenic and lead exposures have been associated with neurotoxicity, which may be linked to epigenetic changes. Our research sought to investigate the correlation between 5mdC and developmental delay (DD) among preschoolers.
View Article and Find Full Text PDFJ Environ Manage
January 2025
College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China. Electronic address:
Cadmium (Cd) is a silvery-white and shiny heavy metal that is common in daily life and can adversely affect the development, lifespan, and reproduction of organisms. In this study, Drosophila melanogaster (F) were cultured from eggs to adults in medium containing different Cd concentrations (0, 2.25, and 4.
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