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Intestinal Colonization of Multidrug-Resistant Organisms: Identification and Antibiotic Susceptibility Patterns of Bacteria Isolated From Healthy Human Fecal Specimens.
Cureus
December 2024
Clinical Microbiology, Prathima Institute of Medical Sciences, Karimnagar, IND.
Introduction Intestinal carriage of multidrug-resistant organisms (MDROs) in healthy populations could amplify resistant bacteria, which may increase the risk of infections by these bacteria in the community and in the hospital. This study investigated the prevalence of colonization of multidrug-resistant (MDR) bacteria in the intestines of healthy individuals in South India. Methods A prospective study was conducted for six months at a tertiary care teaching hospital.
View Article and Find Full Text PDFThe prevalence of multidrug resistance in Staphylococcus hominis isolated from clinical materials.
Sci Rep
January 2025
Department of Pharmaceutical Microbiology and Microbiological Diagnostic, Medical University of Lodz, Łódź, Poland.
The treatment of infections caused by Staphylococcus hominis remains a challenge, mainly due to the increasing resistance of these bacteria to antibiotics. The aim of the study was to determine antibiotic resistance in 62 strains S. hominis isolated from clinical materials, and to identify the molecular basis of resistance to antibiotics.
View Article and Find Full Text PDFClonal dissemination of methicillin-resistant Staphylococcaceae between Algerian sheep farms.
J Glob Antimicrob Resist
December 2024
Division of Molecular Bacterial Epidemiology & Infectious Diseases, Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Switzerland. Electronic address:
Objectives: Sheep farming represents an important economic sector in Algeria, and the potential dissemination of methicillin-resistant Staphylococcaceae (MRS) is a critical veterinary and public health concern. This study aimed to determine the prevalence and types of MRS in ovine in Algeria and characterize them using whole-genome sequencing (WGS) analysis.
Methods: Two hundred sheep from twenty different Algerian farms across three regions were screened for nasal colonization with MRS.
Epidemiological trends for burn wound infections in 2020 in albania.
Ann Burns Fire Disasters
December 2024
Department of Biomedical and Experimental Courses, Faculty of Medicine, University of Medicine, Tirana, Albania.
The burn patient is at high hazard for nosocomial infections (NI) as a result of the nature of the burn damage itself, the immune-compromising impacts of burns, prolonged clinic stays, and intensive diagnostic and therapeutic strategies. The aim of this study is to describe the actual epidemiology of burn wound colonization and infection in the Intensive Care Unit (ICU) of the Service of Burns and Plastic Surgery at the University Hospital Center in Tirana, Albania. The study is retrospective clinical and analytical.
View Article and Find Full Text PDFSwab Testing to Optimize Pneumonia treatment with empiric Vancomycin (STOP-Vanc): study protocol for a randomized controlled trial.
Trials
December 2024
Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Vancomycin, an antibiotic with activity against methicillin-resistant Staphylococcus aureus (MRSA), is frequently included in empiric treatment for community-acquired pneumonia (CAP) despite the fact that MRSA is rarely implicated in CAP. Conducting polymerase chain reaction (PCR) testing on nasal swabs to identify the presence of MRSA colonization has been proposed as an antimicrobial stewardship intervention to reduce the use of vancomycin. Observational studies have shown reductions in vancomycin use after implementation of MRSA colonization testing, and this approach has been adopted by CAP guidelines.
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