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[Effects of interventions to improve compliance with antipsychotic medication in people suffering from schizophrenia-results of recent reviews]. | LitMetric

AI Article Synopsis

  • Non-compliance with antipsychotic medication is a common issue that significantly increases the risk of psychotic relapse and negatively impacts the treatment of schizophrenia.
  • The study reviews meta-analyses from the past few decades on various interventions designed to improve medication adherence among individuals with schizophrenia.
  • The findings indicate that while some interventions, like psychoeducation, have limited effects, others, like cognitive-behavioral and combined interventions, show moderate success in enhancing compliance.

Article Abstract

Background: Non-compliance (or non-adherence) with antipsychotic pharmacotherapy occurs frequently. In addition, there is overwhelming evidence that it constitutes a major risk factor for psychotic relapse. Compliance substantially affects course and treatment of schizophrenia. During the last decades, a large body of research on compliance with antipsychotic medication has been accumulated.

Method: The authors provide an overview of meta-analyses. Reviews published since 1990 on effects of interventions aiming at increasing compliance with medication in people suffering from schizophrenia are summarized.

Results: We found eight reviews which reported empirical findings on the efficacy and effectiveness of interventions with the goal of improving compliance. Interventions have shown limited (psychoeducation) to moderate (cognitive-behavioral and combined interventions) effects. Other relevant findings are summarized and discussed.

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Source
http://dx.doi.org/10.1055/s-2004-828332DOI Listing

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