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Effect of Private Equity Ownership on Access to Outpatient Urologic Cancer Care in Medicare Recipients.
Urology
November 2024
Department of Urology, Division of Health Services Research, University of Pittsburgh Medical Center, Pittsburgh, PA.
Objective: To compare appointment availability and wait times between private equity-owned and non-private equity-owned urology clinics for 2 common urologic complaints.
Methods: We identified all PE-owned urology clinic locations as of June 2022 (n = 390). For each PE-owned location, a geographically matched, non-PE-owned clinic was identified.
First-in-man use of a cardiovascular cell-derived secretome in heart failure. Case report.
EBioMedicine
May 2024
AP-HP, Hôpital Saint-Louis, MEARY Centre for Cell and Gene Therapy, Paris, France; Université Paris Cité, AP-HP, Hôpital Saint-Louis, Clinical Investigation Center in Biotherapies CIC-BT, INSERM, Paris, France.
Background: There is increased evidence that the effects of stem cells can mostly be duplicated by administration of their secretome which might streamline the translation towards the clinics.
Methods: The 12-patient SECRET-HF phase 1 trial has thus been designed to determine the feasibility and safety of repeated intravenous injections of the extracellular vesicle (EV)-enriched secretome of cardiovascular progenitor cells differentiated from pluripotent stem cells in severely symptomatic patients with drug-refractory left ventricular (LV) dysfunction secondary to non-ischemic dilated cardiomyopathy. Here we report the case of the first treated patient (baseline NYHA class III; LV Ejection Fraction:25%) in whom a dose of 20 × 10 particles/kg was intravenously infused three times three weeks apart.
Dickson polynomial-based secure group authentication scheme for Internet of Things.
Sci Rep
February 2024
Department of Computer Science and Engineering, Vardhaman College of Engineering, Hyderabad, India.
Article Synopsis
- The Internet of Things (IoT) is essential for developing smart industrial applications and cities, with a Trusted Authority overseeing communication between IoT devices and infrastructure through security certificates.
- A proposed secure group authentication scheme, based on Dickson polynomials, aims to reduce costs and network traffic while allowing multiple IoT devices owned by different entities to authenticate collectively.
- The system is designed to resist various security threats, utilizes blockchain technology for efficient data transfer, and has been tested on Ethereum's Goerli Testnet, showing improved performance through an analysis of benchmarks.
Access to Sudden Sensorineural Hearing Loss Care at Private Equity-Owned Otolaryngology Clinics.
Otolaryngol Head Neck Surg
June 2024
Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.
Objective: Characterizing access to sudden sensorineural hearing loss (SSNHL) care at private practice otolaryngology clinics of varying ownership models.
Study Design: Cross-sectional prospective review.
Setting: Private practice otolaryngology clinics.
Canada and the pharmaceutical industry in the time of COVID-19.
Int J Soc Determinants Health Health Serv
October 2023
Professor Emeritus, School of Health Policy and Management, York University.
The COVID-19 pandemic showed the close relationship between the Canadian government and the pharmaceutical industry when it came to both domestic and international issues. Domestically, the government chose to prioritize advice about vaccine acquisition from a panel of heavily conflicted people; it signed contracts worth billions of dollars with companies for vaccines but the contents of contracts were largely kept secret. The government also committed over CAD$1 billion in funding for research on COVID-19 but without any requirement that any forthcoming intellectual property or diagnostic and therapeutic products had to be accessible and affordable in low- and middle-income countries (LMICs).
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