[Vaccination failure: case report of Haemophilus influenzae b meningitis in a 14-month-old child].

Pathol Biol (Paris)

Laboratoire de Bactériologie-Virologie-Hygiène Hospitalière, institut de biologie de Nantes, CHU de Nantes, 9 quai Moncousu, 44093 Nantes cedex 01, France.

Published: March 2005

Background: The generalization of the vaccination against H. influenzae b (Hib), according to its integration in the French vaccinal calendar, led to the incidence decrease of the purulent meningitis with Hib in young children, which became a so rare event.

Case Report: We described the case of a 14-months-old child showing a bacterial purulent meningitis with Hib, despite of a well driven vaccination.

Discussion: The epidemiology of bacterial meningitis was upset by the generalization of the anti-H. influenzae b vaccination. The use of combined vaccines specially reduced the incidence and the gravity of this pathology. Nevertheless, in spite of the excellent vaccinal coverage, the limited but real persistence of epiglottis or meningitis due to H. influenzae b should keep in mind of the biologists and the clinicians. Indeed, the chronic nasopharyngal carriage, the existence of not vaccinated or not answering people allow to consider the persistent risk of H. influenzae b bacterial meningitis.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.patbio.2004.02.004DOI Listing

Publication Analysis

Top Keywords

purulent meningitis
8
meningitis hib
8
bacterial meningitis
8
meningitis
6
influenzae
5
[vaccination failure
4
failure case
4
case report
4
report haemophilus
4
haemophilus influenzae
4

Similar Publications

Background: Purulent meningitis poses a significant clinical challenge with high mortality. We present the case of a 54-year-old female transferred to our emergency department with suspected bacterial meningitis, later diagnosed as an Austrian syndrome.

Case Presentation: The patient exhibited subacute somnolence, severe headache, nausea and fever.

View Article and Find Full Text PDF

Purpose: This study aims to explore the underlying causes, diagnostic strategies, and treatment approaches of trauma-induced invasive syndrome (KPIS) through a rare case report. By highlighting the role of trauma as a potential trigger for KPIS, particularly in high-risk populations such as individuals with diabetes, this study seeks to provide valuable insights for improving clinical outcomes and promoting public health awareness.

Background: invasive syndrome is a multi-organ infectious disease commonly associated with complications such as liver abscess, lung abscess, endophthalmitis, and purulent meningitis, with high mortality and disability rates.

View Article and Find Full Text PDF

Acute rhinosinusitis causes more than 30 million patients to seek health care per year in the United States. Respiratory tract infections, including bronchitis and sinusitis, account for 75% of outpatient antibiotic prescriptions in primary care. Sinusitis is a clinical diagnosis; the challenge lies in distinguishing between the symptoms of bacterial and viral sinusitis.

View Article and Find Full Text PDF

Background: Group B streptococcus (GBS) causes neonatal invasive disease, mainly sepsis and meningitis. Understanding the clinical characteristics, laboratory tests, and antibiotic resistance patterns of GBS invasive infections provides reliable epidemiological data for preventing and treating GBS infections.

Methods: Clinical characteristics and laboratory test results from 86 patients with neonatal invasive disease (45 cases of early-onset disease [EOD] and 41 cases of late-onset disease [LOD]) recruited from Fujian Maternity and Child Health Hospital between January 2012 and December 2021 were analyzed.

View Article and Find Full Text PDF

Sexually transmitted proctitis, a prevalent concern among men who have sex with men (MSM) is frequently caused by a range of pathogens, including herpes simplex virus (HSV), and While HSV-associated proctitis typically presents with visible lesions, cases without external manifestations remain evasive. We report the case of an MSM in his early 30s presenting with dyschezia and perineal discomfort after unprotected anoreceptive intercourse. Despite initial inconspicuous findings, rectal swabs revealed HSV-2 infection.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!