[Studies on chemical constituents from root of Hedysarum polybotrys].

Zhongguo Zhong Yao Za Zhi

Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.

Published: May 2004

Objective: To study the chemical constituents of Hedysarum polybotrys.

Method: Chromatographic methods were used to isolate compounds from H. polybotrys and chemical and spectral methods were used to elucidate the structures of the isolated compounds.

Result: Five compounds, N,N,N-trimethyl-tropaphone inner salt (hypaphorine) (1), octadecyl-3-methoxy-4-hydroxy-benzeneacrylate (2), 5,7,4'-trihydroxy-dihydroflavanone 5,7-di-O-beta-D-glucopyranoside (3), 3,4,5-trimethoxy cinnamic acid methy ester (4) and vanillic acid (5), were isolated from the roots of H. polybotrys.

Conclusion: Compounds 1, 2 and 3 were obtained from this plant for the first time, while compounds 1 and 2 were isolated from Hedysarum for the first time.

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