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Analysis of the effectiveness of aspirin in preventing preeclampsia in high-risk pregnant women and the influencing factors of preeclampsia.
Pak J Pharm Sci
March 2025
Obstetrics and Gynaecology, Maternal and Child Health Hospital, Chengdong Avenue, Wujiagang District, Yichang, Hubei Province, China.
This study explores the effect of aspirin on preeclampsia (PE) and analyzes the influencing factors of PE in high-risk pregnant women. We encompassed 110 high-risk pregnant women receiving prenatal examination at Maternal and Child Health Hospital of Yichang City between January 2022 and December 2023, categorized them into the intervention group (n=58,received aspirin therapy), and the control group (n=52, didn't receive pharmaceutical prophylaxis). Clinical and laboratory parameters were compared between groups, with logistic regression performed.
View Article and Find Full Text PDFLeveraging artificial intelligence for inclusive maternity care: Enhancing access for mothers with disabilities in Africa.
Womens Health (Lond)
March 2025
Department of Public Health Medicine, University of KwaZulu-Natal, Durban, South Africa.
Women with disabilities face significant barriers in accessing maternal healthcare, which increases their risk of adverse pregnancy outcomes, particularly in Africa, where resources are limited. Artificial intelligence (AI) presents a unique opportunity to improve inclusivity and accessibility to antenatal care, skilled birth attendance and postnatal care for these women. This paper explores the potential of AI to address the socio-economic, physical, and institutional barriers that limit the utilisation of maternal healthcare services by women with disabilities.
View Article and Find Full Text PDFCharacteristics in patients with unexplained recurrent spontaneous abortion and the impact on immune, coagulation, and inflammatory profiles.
J Matern Fetal Neonatal Med
December 2025
Department of Gynecology and Obstetrics, Xuanwu Hospital, Capital Medical University, Beijing, China.
Objective: Unexplained Recurrent Spontaneous Abortion (RSA) impacts the physical and psychological well-being of women of reproductive age. This study aimed to reveal the potential mechanisms behind unexplained RSA from the perspective of glucose and lipid metabolic profiles before conception and their relationship with immune, coagulation, and inflammatory markers.
Methods: A retrospective analysis was conducted on 100 patients with unexplained recurrent spontaneous abortion at our gynecology department from June 2022 to June 2023.
Effect of carnitine on Hariana bull spermatozoa function after cryopreservation.
Cryo Letters
March 2025
Department of Veterinary Gynaecology and Obstetrics, College of Veterinary Science and Animal Husbandry, Deendayal Upadhayaya Pashu Chikitsa Vigyan Viswavidyalaya Evam Go Anusandhan Sansthan, Mathura, 281001, Uttar Pradesh, India.
Background: Carnitine reduces reactive oxygen species-induced apoptosis and DNA fragmentation through its antioxidant effect.
Objective: To investigate the effect of carnitine on capacitation, mitochondrial activity, acrosomal integrity, reactive oxygen species (ROS), membrane fluidity, and DNA fragmentation during the cryopreservation of Hariana bull spermatozoa.
Materials And Methods: Thirty-two semen ejaculates were obtained using artificial vagina (AV) from four seemingly healthy Hariana bulls.
ZEB1 promotes the immune escape of ovarian cancer through the MCSF-CCL18 axis.
Cancer Cell Int
March 2025
Department of Obstetrics and Gynecology, Zhongda Hospital Jiangbei Branch, School of Medicine, Southeast University, Nanjing, 210048, Jiangsu, China.
This study aimed to determine the molecular mechanisms underlying immune escape in ovarian cancer. Samples of ovarian cancer were used to explore the regulatory pathways involved in the malignant phenotype. Tumor cell models with different levels of factor expression were constructed via transfection, and their regulation was determined through investigation of protein expressions.
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