2-Arylallyl as a new protecting group for amines, amides and alcohols.

Chem Commun (Camb)

Instituto Universitario de Quimica Organometalica "Enrique Moles", Unidad Asociada al C.S.I.C. Julian Claveria, 8, Universidad de Oviedo, 33006-Oviedo, Spain.

Published: February 2005

Amines, amides and ethers containing 2-arylallyl groups are selectively and easily deprotected with tert-butyllithium. This transformation probably involves a carbolithiation reaction of the styrenyl moiety followed by a beta-elimination process.

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http://dx.doi.org/10.1039/b414966aDOI Listing

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