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Similar Publications

Morphine and P2Y12 Inhibitors in ST-Elevation Myocardial Infarction: An Updated Meta-Analysis.

Am J Cardiovasc Drugs

December 2024

Cardiovascular Institute, Detroit Medical Center, Heart Hospital, Wayne State University, 311 Mack Ave, Detroit, MI, 48201, USA.

Background: Morphine is used to control pain in ST-elevation myocardial infarction but reduces P2Y12 inhibition. It is not known if this modulation of platelet inhibition appreciably affects clinical outcomes.

Methods: We screened 979 articles and identified seven studies that met the eligibility criteria for meta-analysis.

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Article Synopsis
  • This study evaluated a hybrid fixation technique (HFT) combining screws and biological support to treat large unstable juvenile osteochondritis dissecans (JOCD) lesions in patients ≤18 years old.
  • Thirteen patients (15 knees) were treated, with evaluations conducted at least one year post-surgery using clinical scales and MRI to assess outcomes and integration of grafts.
  • Results showed high clinical scores, good graft integration, and most patients returned to sports within about 8 months, although some required additional surgery for hardware issues.
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Subclavian arterial rupture due to blunt trauma injury: A case report.

Medicine (Baltimore)

July 2024

Division of Trauma and Critical Care, Department of Surgery, Trauma Center, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.

Rationale: Subclavian arterial injury due to blunt trauma is rare but can have devastating outcomes. Massive hemorrhage or limb ischemia might develop depending on the extent of damage, and open repair might be necessary to salvage the limb. However, life-saving treatments should be prioritized in critically unstable patients.

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Article Synopsis
  • - Free flaps are the top choice for reconstructing defects, and successful surgery relies heavily on microvascular anastomosis, commonly done by hand suturing, though venous couplers are becoming more popular for venous connections.
  • - A case involving a 14-year-old girl with an unstable heel scar and chronic bone infection was treated with a free latissimus dorsi muscle flap, where hand suturing was used for arterial attachment and a venous coupler for the venous connection.
  • - Unfortunately, the venous coupler unexpectedly opened before closing the wound, leading to a crisis; the team salvaged the situation by manually completing the anastomosis while leaving the coupler rings in place, resulting
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Here we present a novel adaptation of the previously described fibula pro-tibial fixation in a case requiring salvage fixation of a bimalleolar ankle fracture in an osteoporotic patient. Unstable osteoporotic ankle fractures are a challenging injury to manage and typically occur in a frail and comorbid subgroup of patients. Various techniques have been described in the evolution of managing these injuries, e.

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