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Clinical and Multimodal Imaging Study to Differentiate Amelanotic Choroidal Lesions.
Ocul Oncol Pathol
December 2024
Anant Bajaj Retina Institute, L V Prasad Eye Institute, Hyderabad, India.
Introduction: The aim of this study was to differentiate amelanotic choroidal lesions - amelanotic choroidal melanoma, choroidal metastasis, and choroidal granuloma using multimodal imaging.
Methods: Retrospective comparative chart review was done. Patients diagnosed with the abovementioned choroidal lesions from 2015 to 2022 were included.
Paradoxical Reaction in Intraocular Tuberculosis: Report of Three Cases.
Ocul Immunol Inflamm
December 2024
Faculdade de Medicina, LIM 33, Department of Ophthalmology, Universidade de São Paulo, São Paulo, Brazil.
Purpose: To present paradoxical reaction (PR) in three cases with ocular tuberculosis (OTB) treated with antitubercular therapy (ATT), highlighting diagnostic challenges and treatment strategies.
Methods: We retrospectively reviewed clinical records of three OTB patients presenting with paradoxical worsening after ATT initiation at two Brazilian university hospitals.
Results: The patients (2 males, 1 female) experienced worsening clinical presentation (increased inflammation, vision loss) within two to three weeks after initiating ATT.
Clinical Features and Predictors of Treatment Outcome in Patients with Ocular Tuberculosis from the Netherlands and Indonesia: The OculaR TB in Low versus High Endemic Countries (ORTEC) Study.
Ocul Immunol Inflamm
May 2024
Department of Internal Medicine Section Allergy and Clinical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Article Synopsis
- The study compares ocular tuberculosis (OTB) patients in the Netherlands, a low TB-endemic country, with those in Indonesia, a high TB-endemic country, focusing on clinical features, treatment approaches, and outcomes.
- Indonesian patients exhibited more severe symptoms and complications, such as higher rates of blindness and acute uveitis, while both groups had similar overall treatment success rates.
- Key predictors of poor treatment response included the presence of severe anterior chamber cells, specific types of eye lesions, and retinal vasculitis at the start of treatment.
A case of solitary choroidal tuberculoma with highly positive tuberculin skin test and negative interferon gamma release assays.
Int J Ophthalmol
May 2024
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
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