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Relation of aneurysmectomy in patients with advanced left ventricular remodeling to postoperative left ventricular filling pressure, redilatation with ischemic mitral regurgitation. | LitMetric

AI Article Synopsis

  • A study on 14 patients who underwent surgical LV aneurysmectomy measured LV volume and mitral parameters to assess complications post-surgery.
  • Late mitral regurgitation (MR) occurred in 36% of patients within 3 to 6 months post-op, linked to more severe preoperative heart conditions.
  • Patients with late MR displayed worse postoperative diastolic function and greater increases in LV volume after surgery, indicating that advanced heart remodeling before surgery may lead to complications like MR later on.

Article Abstract

Left ventricular (LV) volume, mitral E deceleration time, and mitral regurgitation (MR) fraction were measured by echocardiography in 14 patients with surgical LV aneurysmectomy. Late MR developed 3 to 6 months after surgery in 5 of the 14 patients (36%). Compared with patients without late MR, those with late MR had a significantly greater preoperative LV end-diastolic volume index (LVEDVI) (134 +/- 21 vs 93 +/- 19 ml/m(2), p <0.01), surgical reduction in LVEDVI (-51 +/- 14 vs -20 +/- 16 ml/m(2), p <0.01), early postoperative LV diastolic dysfunction with shortened mitral E deceleration time (106 +/- 23 vs 141 +/- 24 ms, p <0.01), and a late postoperative reincrease in LVEDVI (+28 +/- 4 vs +3 +/- 8 ml/m(2), p <0.01), suggesting that surgical LV aneurysmectomy in patients with advanced preoperative LV remodeling may result in postoperative LV diastolic dysfunction, promoting later LV redilation with ischemic MR.

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Source
http://dx.doi.org/10.1016/j.amjcard.2004.10.024DOI Listing

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