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Otoscleroma of the Middle Ear and Mastoid Cavity with Facial Palsy: A Case Report.
Iran J Otorhinolaryngol
January 2025
Department of Otorhinolaryngology, Faculty of Medicine, Alexandria University, Egypt.
Introduction: Scleroma is a chronic, specific granulomatous disease that affects the head and neck mucosa. Its common sites are the nose and larynx; however, it might affect other areas. One of the rare sites to be affected is the middle ear and mastoid cavity, for which the term otoscleroma was coined.
View Article and Find Full Text PDFPrimary Subglottic Laryngeal Tuberculosis Mimicking as Malignancy: A rare case Report.
Indian J Otolaryngol Head Neck Surg
December 2024
Deptt of Otorhinolaryngology and head and neck surgery, GMC, Rajindra Hospital, Patiala, India.
Article Synopsis
- Primary laryngeal tuberculosis is rare, with less than 1% incidence, while secondary laryngeal TB is more common and typically originates from the lungs.
- The case described involves a 31-year-old woman with persistent throat irritation, hoarseness, and mild respiratory issues, ultimately diagnosed with primary subglottic tuberculosis.
- This case is noteworthy due to the rarity of primary laryngeal TB, which can sometimes be mistaken for cancer.*
Invasive Fungal Laryngotracheitis Causing Laryngotracheal Separation.
Cureus
October 2024
Department of Otorhinolaryngology, Hospital Shah Alam, Shah Alam, MYS.
Fungal laryngotracheitis (FLT) is rare, and the diagnosis can be challenging, as its presentation lacks specificity and may resemble other conditions such as granulomatous disease, gastroesophageal reflux, or malignancy. FLT can be very invasive, causing complete laryngotracheal separation, leading to a non-functioning larynx. We report a 39-year-old Indian woman with diabetes who presented to the emergency department with a sore throat, hoarseness, dysphagia, and stridor for two days.
View Article and Find Full Text PDFRare Case of Laryngeal Histoplasmosis: A Diagnostic Challenge.
Indian J Otolaryngol Head Neck Surg
October 2024
Department of Otorhinolaryngology, Mahatma Gandhi Medical college, Jaipur, Rajasthan, 302033 India.
Granulomatous lesions, though rare, can affect diverse body regions, including the larynx, presenting diagnostic challenges. In India, where malignancy and tuberculosis prevail, fungal infections are often overlooked. We present a case of 34 year old male with complaint of change in voice which was approached as malignancy but later turned out to be histoplasmosis on histopathology.
View Article and Find Full Text PDFJAK-inhibitor Tofacitinib in Severe Laryngeal Sarcoidosis: A Case Report.
Laryngoscope
February 2025
Royal Brompton Hospital London, Guy's, and St Thomas' NHS Foundation Trust, London, UK.
Sarcoidosis is an inflammatory, non-caseating granulomatous multisystem disease associated with JAK-STAT (Janus kinases-signal transducer and activator of transcription proteins) pathway activation. We present a patient with severe multi-systemic sarcoidosis who showed marked improvement with tofacitinib with regards to pulmonary, cutaneous, nasal and laryngeal disease. Tofacitinib prevented critical laryngeal stenosis from progressing to tracheostomy, induced regression of cutaneous lesions and improved pulmonary function in this steroid-resistant and immunosuppressive intolerant case.
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