We propose new two and k-sample tests for evaluating the equality of survival distributions against alternatives that include crossing of survival functions, and proportional and monotone hazard ratios. The tests allow for right censored data. The asymptotic power against local alternatives is investigated. Simulation results demonstrate that the new tests are more powerful than known tests when survival functions cross. We apply the tests to a well known study of chemo- and radio-therapy conducted by the Gastrointestinal Tumor Study Group. The P-values for both proposed tests are much smaller than for other known tests.
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http://dx.doi.org/10.1007/s10985-004-4777-7 | DOI Listing |
J Neurosurg Pediatr
January 2025
Departments of1Neurosurgery and.
Objective: Intraventricular baclofen (IVB) administration is used for the treatment of secondary dystonia associated with cerebral palsy (CP), but it has not been reported as a first-line infusion technique for spasticity. In this study, the authors report outcomes of patients with mixed or isolated spasticity treated with IVB administration.
Methods: A retrospective analysis was performed of consecutive patients treated with IVB between 2019 and 2023.
Phys Rev Lett
December 2024
Center for Computational Astrophysics, Flatiron Institute, 162 5th Avenue, New York, New York 10010, USA.
High-energy extensions to general relativity modify the Einstein-Hilbert action with higher-order curvature corrections and theory-specific coupling constants. The order of these corrections imprints a universal curvature dependence on observations while the coupling constant controls the deviation strength. In this Letter, we leverage the theory-independent expectation that modifications to the action of a given order in spacetime curvature (Riemann tensor and contractions) lead to observational deviations that scale with the system length scale to a corresponding power.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Department of Basic Science, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.
Work extraction is one of the most central processes in quantum thermodynamics. However, the prior analysis of optimal extractable work has been restricted to a limited operational scenario where complete information about the initial state is given. Here, we introduce a general framework of black box work extraction, which addresses the inaccessibility of information on the initial state.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Departement de Physique Theorique, Universite de Geneve, 24 quai Ernest Ansermet, 1211 Geneve 4, Switzerland.
We consider resonant wavelike dark matter conversion into low-frequency radio waves in the Earth's ionosphere. Resonant conversion occurs when the dark matter mass and the plasma frequency coincide, defining a range m_{DM}∼10^{-9}-10^{-8} eV where this approach is best suited. Owing to the nonrelativistic nature of dark matter and the typical variational scale of the Earth's ionosphere, the standard linearized approach to computing dark matter conversion is not suitable.
View Article and Find Full Text PDFDiagnosis (Berl)
January 2025
Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Objectives: To examine factors impacting diagnostic evaluation of suspected deep vein thrombosis (DVT) by analyzing the test ordering patterns and provider decision-making within a universal health coverage system in Hungary.
Methods: We analyzed test orders for suspected DVT between 2007 and 2020, and the financial framework influencing diagnostic practices. An anonymous survey was also conducted among Emergency Department physicians to explore factors influencing diagnostic decision-making.
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