Purpose Of Review: The small bowel has been a difficult organ for gastroenterologists to evaluate. Small bowel radiographs and CT scanning have not had a high diagnostic rate, especially in patients presenting with small bowel bleeding. The video capsule "endoscope" has allowed for the direct visualization of the small bowel mucosa. This new technique provides direct viewing of the entire small bowel much like conventional endoscopy.
Recent Findings: A series of studies have shown that video capsule endoscopy (VCE) is superior to barium radiography studies, CT scanning, and push enteroscopy for diagnosing disorders of the small bowel. Numerous case reports of angioectasias, Crohn disease, small bowel tumors, and other small bowel disorders have been reported. A recent study proposes that VCE helped to direct therapy and had a great impact in patient care.
Summary: Capsule endoscopy provides higher rates and more accurate diagnosis of small bowel diseases. The future of this technology could improve the ability to visualize the small bowel and improve the treatment of patients with small bowel disorders.
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http://dx.doi.org/10.1097/00001574-200409000-00010 | DOI Listing |
World J Gastroenterol
January 2025
Department of Surgery, University Hospital of Larissa, Larissa 41334, Greece.
Autoimmune enteropathy (AIE) is a rare immune mediated disorder primarily affecting children, characterized by chronic diarrhea, malabsorption, vomiting, weight loss and villous atrophy. It has also been observed in adults presenting diagnostic and treatment challenges due to its overlap with other gastrointestinal disorders such as celiac disease. Initial diagnostic criteria for AIE include small bowel villous atrophy, lack of response to dietary restrictions, presence of anti-enterocyte antibodies, and predisposition to autoimmunity without severe immunodeficiency.
View Article and Find Full Text PDFPrz Menopauzalny
December 2024
Department of Surgery, General University Hospital of Patras, Greece.
Small bowel obstruction (SBO) is a serious condition with distinct symptoms such as constipation, vomiting, and abdominal distension. It is commonly caused by well-recognised factors. Recent advancements in imaging techniques and minimally invasive procedures have significantly improved our ability to accurately select patients for surgical intervention and promptly identify common SBO causes.
View Article and Find Full Text PDFAim Of The Study: This study investigated the mechanism by which the Postoperative Tongqi Formula (PTQF) treats postoperative ileus (POI) through regulation of the p38 MAPK signaling pathway, Zona occludens 1 (ZO-1) protein, and metabolism.
Methods: The primary components of PTQF were characterized using UHPLC-Q-TOF-MS/MS. The identified compounds subsequently employed network pharmacology to predict the signaling pathways associated with the inflammatory phase of POI.
Cureus
December 2024
General Surgery, Local Health Unit of Alto Minho, Viana do Castelo, PRT.
Meckel's diverticulum (MD) is the most common congenital anomaly of the gastrointestinal tract, arising from incomplete obliteration of the vitelline duct. MD contains all layers of the intestinal wall and often remains asymptomatic. Gastrointestinal bleeding, bowel obstruction, and acute diverticulitis occur in a few cases.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Department of Radiology, School of medicine, college of medicine and health science, Bahir Dar University, Bahir Dar, Ethiopia.
Neurofibromatosis type 1 (NF1) is characterized by café-au-lait patches on the skin and the presence of neurofibromas. Gastrointestinal stromal tumor (GIST) is the most common GI tumour in NF1 patients. In NF1-associated GIST, KIT and PDGFRA mutations are frequently absent and imatinib is ineffective.
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