[Corneal precipitation of fluoroquinolones with magnesium].

Ann Biol Clin (Paris)

Service de biochimie, Centre hospitalier Pasteur, Colmar.

Published: March 2005

Infrared spectrophotometric analysis (FTIR) was performed on a crystalline deposit developed in a corneal ulcer by an old woman who received ciprofloxacine ophthalmic drops. We collected the data of the literature on the subject. After in vitro crystallization experiments, we conclude that ciprofloxacin and norfloxacin corneal precipitates occur at physiological lachrymal pH with magnesium.

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