The local anaesthetic domain, very often implicated in the dental practice, it's in to a continuously progress from two points of view: the development of the products proposal and the improvement of the pharmacokinetic parameters. In our study we presented: new classifications of local anaesthetics, their characteristics and structure, the pharmacokinetic and pharmacodynamic parameters of local anaesthetics used in dental practice. An interesting remark of last years is represented by the fact that the local anaesthetics could also have an antibacterial effect which is often helpful in dental practice.
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J Clin Med
January 2025
Department of Oral and Maxillofacial Surgery, University Hospital of Salzburg, Paracelsus Medical University, 5020 Salzburg, Austria.
: Defects in maxillary and mandibular continuity are common in maxillofacial practice. They can occur after trauma, osteonecrosis, congenital jaw deformities, or surgical resection of benign or malignant tumours. Reconstruction with microvascular bone flaps and subsequent prosthetic rehabilitation is considered the contemporary first line treatment.
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Periodontal Diseases and Oral Mucosa Diseases, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.
: Conventional treatments for cancers of the head and neck region are often associated with high recurrence rates and impaired quality of life. Photodynamic therapy (PDT) has emerged as a promising alternative, leveraging photosensitizers such as hypericin to selectively target tumour cells with minimal damage to surrounding healthy tissues. : We aimed to evaluate the efficacy and underlying mechanisms of hypericin-mediated PDT (HY-PDT) in treating head and neck cancers.
View Article and Find Full Text PDFInt J Environ Res Public Health
December 2024
Department of Family Practice, Midwifery Program, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Research demonstrates associations between oral health and specific mental health conditions in the general population, yet these relationships remain understudied during pregnancy, despite pregnancy's profound effects on both oral and psychological well-being. Our rapid review examines current evidence on associations between oral health conditions and psychological states (anxiety, depression, and stress) during pregnancy, aiming to inform and strengthen integrated prenatal care strategies. Following PRISMA-RR guidelines, we conducted a systematic search on OVID Medline, CINAHL, and PsycINFO (January 2000-November 2024) for studies examining relationships between oral health conditions (periodontal disease, dental caries) and psychological status during pregnancy and up to one year postpartum.
View Article and Find Full Text PDFInt J Environ Res Public Health
December 2024
Pharmacotherapy Department, College of Pharmacy, University of North Texas Health Sciences Center, Fort Worth, TX 76107, USA.
Inflation generates stress, which may lead to high rates of anxiety and depression. Given the recent surge and subsequent decline in the inflation rate in the United States, the prevalence of stress due to inflation may vary, as well as its relationship with anxiety and depression. Therefore, we investigated the prevalence of stress due to inflation and its association with anxiety and depression over time among working-age adults in the United States.
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, Faculty of Dentistry, Taif University, Taif 21944, Saudi Arabia.
In Saudi Arabia, dental trauma is regarded as one of the most important issues affecting schoolchildren. This study evaluated Saudi Arabian schoolteachers' knowledge, attitude, and practice regarding emergency dental trauma management. A cross-sectional study was conducted on 263 schoolteachers from 25 schools; 50.
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