The animals were overheated in thermal chamber for the period of 4 hours at 37 degrees C. Though the water intake was not limited, the rats developed the state of dehydration accompanied by weight loss, redistribution of water and electrolytes in tissues and decrease of circulation plasma volume. Intragastric probe water administration in the quantity equal to the weight loss led to partial rehabilitation of the initial indexes, however full rehabilitation of water-electrolyte balance was observed while administering hypotonic salt solution. The conclusion is made that in case of water rehydration a disorder of water-salt exchange of kidney mechanisms regulation is observed and it is advisable to use hypotonic salt solutions to achieve quick rehydration effect.

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