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Devastating presentations of regional enteritis (Crohn's disease): two reports of survival following severe multiple organ dysfunction syndrome. | LitMetric

AI Article Synopsis

  • Regional enteritis, also known as Crohn's disease, can show a wide range of symptoms, from mild to severe.
  • The text discusses two specific cases where regional enteritis led to dangerous complications: one case involved Clostridium perfringens sepsis, and the other was linked to hemolytic-uremic syndrome, both resulting in life-threatening organ failure.
  • Despite the high predicted risk of mortality, both patients recovered after receiving surgical intervention and intensive care, highlighting that severe cases of regional enteritis can have positive outcomes.

Article Abstract

Background: Regional enteritis may present in the setting of a variety of clinical symptoms. These symptoms range from mild to severe.

Methods: Here we describe two different presentations of regional enteritis (Crohn's disease): one in the setting of Clostridium perfringens sepsis and the second in association with hemolytic-uremic syndrome. Both presentations resulted in life-threatening multiple organ dysfunction syndrome.

Results: Following appropriate surgical management and intensive physiologic support, both patients recovered, despite a MODS-predicted risk of mortality of 100% and 91%, respectively.

Conclusions: Fulminant presentations of regional enteritis of this magnitude are rare, and highlight the resolution of severe multiple organ dysfunction for each presentation.

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Source
http://dx.doi.org/10.1089/sur.2004.5.301DOI Listing

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