The development of research with children highlights a number of ethical issues for the research process concerning consent, confidentiality and protection from harm. This article aims to analyse the extent to which these issues have been considered within the published guidance for research involving children. Several key principles emerged: there is consensus that it is unethical not to conduct research with children; consent should be obtained from both the child and the parent or guardian; where the child does not have sufficient understanding of what is involved and the implications of such involvement, the assent of the child should be sought; children involved in research should be made aware that, where information concerning risks to themselves or others emerges, confidentiality cannot be guaranteed; and finally researchers must consider the potential impact of research participation on the child, building methods of providing support to children into the research proposal.
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http://dx.doi.org/10.1177/1367493505049646 | DOI Listing |
Histol Histopathol
January 2025
Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga, Punjab, India.
Autism spectrum disorder (ASD) is a globally recognized neurodevelopmental condition characterized by repetitive and restrictive behavior, persistent deficits in social interaction and communication, mental disturbances, etc., affecting approximately 1 in 100 children worldwide. A combination of genetic and environmental factors is involved in the etiopathogenesis of the disease, but specific biomarkers have not yet been identified.
View Article and Find Full Text PDFJ Int Med Res
January 2025
Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Objective: To evaluate whether there is an association between maternal mental health, purchase of psychotropic drugs, socioeconomic status and major congenital anomalies in offspring.
Methods: A register-based cohort study of 6189 Finnish primiparous women who had a singleton delivery between 2009 and 2015. Data on pregnancy and delivery outcomes, psychiatric diagnosis, prescription drug purchases and offspring congenital anomalies were obtained from Finnish national registers.
Aliment Pharmacol Ther
January 2025
Department of Internal Medicine IV (Gastroenterology, Hepatology and Infectious Diseases), Jena University Hospital, Friedrich-Schiller-University, Jena, Germany.
Background: Transjugular intrahepatic portosystemic shunt (TIPS) placement leads to a reduction in portal pressure and an improvement in survival in patients with recurrent and refractory ascites and variceal haemorrhage. Prediction of post-TIPS survival is primarily determined by factors identified before the TIPS procedure, as data collected during or after TIPS implantation are limited. The aim of the study was to evaluate the influence of early hemodynamic changes after TIPS placement on survival, in order to refine post TIPS management.
View Article and Find Full Text PDFActa Paediatr
January 2025
Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
J Health Serv Res Policy
January 2025
Assistant Professor, Department of Psychology, University of California Los Angeles, Los Angeles, CA, USA.
Objective: This study examined whether being scheduled in a screening clinic versus scheduled directly with a long-term provider to conduct a mental health intake (MHI) is associated with engagement in child psychiatry services in New England, USA.
Method: We used electronic medical record data from one safety-net hospital serving a predominantly low-income and minoritised population. The study sample included 815 youths aged 0 to 25 years, referred or scheduled for a MHI between 1 January 2016 and 31 December 2016.
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