A 79-year-old nursing home resident who was taking olanzapine presented to multiple hospitals with fevers of unknown origin. After an extensive workup to rule out infection, the patient was diagnosed as having neuroleptic malignant syndrome (NMS). This patient's presentation was atypical because of the lack of rigidity or tremor at the time of admission. This case highlights the importance of including NMS in the differential diagnosis of fever of unknown origin in medical patients. A review of the medical literature is taken, focusing on diagnoses, prevalence, predisposing factors, pathophysiology, and current treatment approaches for NMS.
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http://dx.doi.org/10.1097/01.SMJ.0000145285.28124.66 | DOI Listing |
Clin Res Hepatol Gastroenterol
January 2025
NMC Royal Hospital, Khalifa City, Abu Dhabi, United Arab Emirates.
gastrointestinal bleeding, colonic varices, lower gastrointestinal bleeding.
View Article and Find Full Text PDFMar Pollut Bull
January 2025
Universidade Federal de Pernambuco, Programa de Pós-Graduação em Biologia Animal, Center for Biosciences, Av. Prof. Morais Rêgo s/n, Recife, Pernambuco 50670-420, Brazil; Universidade Federal de Pernambuco, Department of Zoology, Center for Biosciences, Av. Prof. Morais Rêgo s/n, Recife, Pernambuco 50670-420, Brazil. Electronic address:
During the last half of 2019, the Northeast coast of Brazil suffered from an extensive oil spill of unknown origin, and marine organisms in those areas were subjected to significant impacts. In situations like this, the contaminant effects can persist for varying periods. Oil contaminants, such as polycyclic aromatic hydrocarbons (PAHs), generally reduce taxa's abundance and diversity in benthic communities in areas with greater exposure to chemical components.
View Article and Find Full Text PDFBr J Hosp Med (Lond)
January 2025
Department of Rheumatism and Immunity, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Patients receiving kidney transplant experience immunosuppression, which increases the risk of bacterial, viral, fungal, and parasitic infections. Q fever is a potentially fatal infectious disease that affects immunocompromised renal transplant recipients and has implications in terms of severe consequences for the donor's kidney. A patient with acute Q fever infection following kidney transplantation was admitted to the Tsinghua Changgung Hospital in Beijing, China, in March 2021.
View Article and Find Full Text PDFJ Clin Med
January 2025
Institute of Infectious Diseases and Infection Control, Jena University Hospital, Friedrich-Schiller-University Jena, 07747 Jena, Germany.
: Despite recent decades' rapid advances in the management of patients with sepsis and septic shock, global sepsis mortality and post-acute sepsis morbidity rates remain high. Our aim was, therefore, to provide a first overview of sepsis care pathways as well as barriers and supportive conditions for optimal pre-clinical, clinical, and post-acute sepsis care in Germany. : Between May and September 2023, we conducted semi-structured, video-based, one-to-one pilot expert interviews with healthcare professionals representing pre-hospital, clinical, and post-acute care settings.
View Article and Find Full Text PDFJ Clin Med
January 2025
Eye Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg im Breisgau, Germany.
: Clinically inactive corneal scars have repeatedly been shown to exhibit histological inflammation. This study aimed to evaluate the degree of histological inflammation in clinically inactive corneal scars of different origins and its correlation with graft rejection and failure following penetrating keratoplasty. : The study included 205 primary corneal explants with clinically inactive central scars resulting from herpes simplex virus keratitis (HSV, = 55), keratoconus ( = 39), mechanical trauma ( = 27), scrophulosa ( = 22) or other/unknown causes ( = 62).
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