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Microencapsulation of Essential Oils and Oleoresins: Applications in Food Products.
Foods
November 2024
Instituto Nacional de Investigação Agrária e Veterinária (INIAV), Av. da República, Quinta do Marquês, 2780-157 Oeiras, Portugal.
Essential oils (EOs) and oleoresins (ORs) are plant-derived extracts that contain both volatile and non-volatile compounds used for flavoring, coloring, and preservation. In the food industry, they are increasingly used to replace synthetic additives, aligning with consumer demand for natural ingredients, by substituting artificial flavors, colorants, and preservatives. Microcapsules can be added to a vast range of foods and beverages, including bakery products, candies, meat products, and sauces, as well as active food packages.
View Article and Find Full Text PDFAlginate-based microencapsulation as a strategy to improve the therapeutic potential of cannabidiolic acid.
Int J Pharm
December 2024
Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Química y Metabolismo del Fármaco (IQUIMEFA), Facultad de Farmacia y Bioquímica, Argentina; Instituto de Ciências Biológicas (ICB), Universidade Federal do Rio Grande - FURG, Rio Grande, RS, Brazil. Electronic address:
Cannabidiolic Acid (CBDA) is a promising natural compound with potent antioxidant, anti-inflammatory, and anti-emetic properties. Its antioxidant activity rivals that of vitamin E, while its anti-inflammatory effects are also remarkable. Additionally, CBDA has been shown to effectively reduce nausea and emetic attacks.
View Article and Find Full Text PDFAssessing Novel Antibody-Based Therapies in Reconstructive 3D Cell Models of the Tumor Microenvironment.
Adv Biol (Weinh)
December 2024
iBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, Oeiras, 2780-901, Portugal.
Targeted, combinatorial, and immunomodulatory therapies, such as antibody-drug conjugates (ADCs) and immunomodulatory antibodies (Abs), are powerful weapons against tumor cells and immune cells within the tumor microenvironment (TME). Therefore, the evaluation of such therapies should be conducted in pre-clinical models able to recapitulate the complex cellular and molecular crosstalk of the TME. To build-in critical hallmarks of the TME, a breast cancer heterotypic 3D cell model (3D-3) is devised using a microencapsulation strategy with an inert biomaterial (alginate) and agitation-based cultures.
View Article and Find Full Text PDFCurrent State of Scientific Knowledge on Curcumin Encapsulation and Applications.
Recent Adv Food Nutr Agric
October 2024
Laboratory of Natural Products Chemistry and Biomolecules, Faculty of Sciences, Saad Dahlab University of Blida 1- POB 270, Soumaa Road, Blida, Algeria.
Article Synopsis
- Curcumin, a yellow pigment known for its anti-inflammatory and antioxidant properties, has been associated with various health benefits for diseases like diabetes, cancer, and more.
- Despite its benefits, curcumin faces challenges such as low bioavailability and degradation under certain conditions, prompting research into micro-encapsulation techniques to enhance its stability and solubility.
- This review explores different shell materials and methods for microencapsulating curcumin, along with its applications in food, medicine, and cosmetics, while also discussing recent research findings and future challenges in the field.
Microencapsulation of and within a Novel Polysaccharide-Based Core-Shell Formulation: Improving Probiotic Viability and Mucoadhesion.
ACS Biomater Sci Eng
November 2024
School of Chemical and Biomolecular Engineering, Faculty of Engineering, The University of Sydney, Sydney, New South Wales 2006, Australia.
Probiotics health benefits are hampered by long-term storage, gastrointestinal transit, and lack of adequate colonization within the colon. To this end, we have designed a core-shell structure that features an acid resistant core formulation with low water activity composed of alginate, hydroxypropyl methyl cellulose, and gellan gum (AHG) and a mucoadhesive shell made from chemically modified carboxymethyl chitosan with polyethylenimine (PEI-CMC). The structure of the core-shell microparticles was examined using scanning electron microscopy, and rheological measurements confirmed the improved ionic interactions between the core and the shell using the PEI-modified CMC.
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