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Mechanisms of exercise-related neurocardiogenic syncope and the relationship between resting and dynamic cardiac testing.
Cardiol Young
January 2025
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Objective: Syncope is common among pediatric patients and is rarely pathologic. The mechanisms for symptoms during exercise are less well understood than the resting mechanisms. Additionally, inert gas rebreathing analysis, a non-invasive examination of haemodynamics including cardiac output, has not previously been studied in youth with neurocardiogenic syncope.
View Article and Find Full Text PDFArrhythmogenic right ventricular cardiomyopathies: Diagnostic challenges from imaging to genetics.
Kardiol Pol
January 2025
Department of Cardiology, University of Medicine and Pharmacy 'Carol Davila', Bucharest, Romania.
Article Synopsis
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic heart condition mainly found in young males, with variations in severity seen in females, who may show milder symptoms or be diagnosed later in life.
- Some individuals may not show symptoms, while others might experience serious issues like sudden cardiac death, which can occur unexpectedly.
- Diagnosis involves thorough investigations including imaging, ECGs, and genetic testing, with emphasis on recognizing risk factors and family history, while also ensuring proper counseling for patients regarding the limits of genetic testing.
Exercise-induced complete atrioventricular block resulting in cardiac arrest: a case report and review of diagnostic strategies.
Eur Heart J Case Rep
July 2024
Graduate Program in Cardiology and Cardiovascular Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Background: Exercise-induced complete atrioventricular block (EIAVB) is a rare cardiac conduction abnormality presenting challenges in diagnosis due to non-specific symptoms such as exertional dyspnoea, dizziness, and syncope.
Case Summary: We present a case of a 76-year-old female with recurrent exercise-associated syncope. Non-invasive exercise testing played a crucial role in diagnosing her condition, revealing EIAVB and underscoring its importance in patients with cardiovascular risk factors.
Clinical Application of Exercise Stress Echocardiography in an Outpatient Pediatric Population.
J Clin Med
April 2024
Heart Center do Hospital da Cruz Vermelha, 1500-048 Lisboa, Portugal.
Article Synopsis
- Exercise stress echocardiography (ESE) is viable for children, with a 100% success rate in a study involving 309 children aged 6-17.
- Most participants were symptomatic, and a significant number (39%) showed important intraventricular gradients (IVG) during testing.
- While regional wall motion abnormalities (RWMAs) were limited, the findings suggest that ESE can effectively replicate symptoms, especially in those with IVG.
Electrophysiological Characteristics and Ablation Outcomes in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia.
J Am Heart Assoc
December 2023
Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China.
Background: Catheter ablation of premature ventricular contractions (PVCs) that trigger polymorphic ventricular tachycardia (PVT) or ventricular fibrillation has been reported as a novel therapy to reduce the syncope events in patients with catecholaminergic PVT, whereas the long-term ablation outcome and its value in improving exercise-induced ventricular arrhythmias remain unclear.
Methods And Results: Fourteen consecutive selected patients with catecholaminergic PVT (mean±SD age, 16±6 years; 43% male patients) treated with maximum β-blockers with no possibility of adding flecainide were prospectively enrolled for catheter ablation. The primary end point was syncope recurrence, and the secondary end point was the reduction of the ventricular arrhythmia score during exercise testing.
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