AI Article Synopsis

  • The study aimed to evaluate the effectiveness of the gonadotrophin-releasing hormone agonist Dipherelin in treating women with endometriosis-related fertility issues.
  • 164 patients were analyzed, with one group receiving Dipherelin for 3 months and another for 6 months, measuring outcomes like pain levels, pregnancy rates, and side effects.
  • Results indicated that Dipherelin 3.75 mg is an effective treatment for infertility caused by endometriosis, significantly improving patient conditions.

Article Abstract

Objective: To determinate the effectiveness of treatment with gonadotrophine releasing hormone agonist.

Methods: We investigated 164 patients with laparoscopy divided in two groups. Women in first group received Dipherelin 3. 75 mg /lpsen/ for 3 months. Second group had received Dipherelin 3.75 mg for 6 months. Preparation was done i.m. every 28 days. All patients in the study had endometriosis grade I-II using the AFS classification after laparoscopy. The measures according to compare in the 2 groups was as following: 1. Dysmenorhoea, dyspareunia and pelvic pain before and after treatment. 2. Rate of pregnancy. 3. Bleeding during the treatment. 4. Amenorhoea after treatment.

Conclusions: After analysis of the patients in the 2 groups we decided that Dipherelin 3.75 mg is an effective treatment of sterility related to endometriosis.

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