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Creation of a Tibia Extension Model With a Perforated Ilizarov Ring System: An Experimental Study in Rats.
Cureus
December 2024
Department of Orthopaedics and Traumatology, Gaziantep University Faculty of Medicine, Gaziantep, TUR.
Distraction osteogenesis is a valuable clinical technique used to address length discrepancies in long bone deformities. This procedure involves performing an osteotomy at an appropriate site in the bone and correcting the deformity through an extension system. This research aims to investigate the efficacy of a newly developed device for use in rat tibias and to provide an alternative to existing devices used in animal experiments.
View Article and Find Full Text PDFThe pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes.
Nat Metab
January 2025
Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Bone lengthening and fracture repair depend on the anabolic properties of chondrocytes that function in an avascular milieu. The limited supply of oxygen and nutrients calls into question how biosynthesis and redox homeostasis are guaranteed. Here we show that glucose metabolism by the pentose phosphate pathway (PPP) is essential for endochondral ossification.
View Article and Find Full Text PDFFocused Investigation of Facial Nerve Dysfunction After Mandibular Distraction Osteogenesis for Robin Sequence.
J Craniofac Surg
January 2025
Division of Plastic and Reconstructive Surgery, Children's National Hospital.
Facial nerve dysfunction (FND) is a well-recognized but poorly documented complication of mandibular distraction osteogenesis (MDO) for Robin sequence (RS). This study aims to document the authors' experiences with FND and identify risk factors associated with this adverse event. A retrospective review of a prospectively gathered database was performed to identify patients with RS who underwent MDO at the authors' institution from March 2016 to June 2023.
View Article and Find Full Text PDFShort-term outcomes of gradual ulnar lengthening in multiple hereditary osteochondromas of the forearm with monolateral external fixator.
J Pediatr Orthop B
January 2025
Trauma Research Center, Rajaee (Emtiaz) Trauma Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Hereditary multiple exostoses is an autosomal dominant genetic condition primarily affecting long bones. Forearm deformities, including wrist ulnar deviation, ulnar shortening, radial or ulnar bowing, and radial head dislocation, are common manifestations. Gradual ulnar lengthening is suggested as a viable treatment option for managing these deformities.
View Article and Find Full Text PDFDigital Analysis of Dentogingival Factors Influencing the Gingival Margin Position in the Esthetic Zone.
J Esthet Restor Dent
January 2025
Center of Advanced Dental Education, Department of Periodontics, Saint Louis University, Saint Louis, Missouri, USA.
Objectives: To investigate the correlation between gingival thickness (GT) and buccal bone thickness (BBT), as well as the effects of GT, BBT, bone crest level (BC), and tooth position on the buccal gingival margin location of maxillary teeth in the esthetic zone.
Materials And Methods: Periodontally healthy subjects with prior cone beam computed tomography and intraoral scans for dental implant planning were included. The hard and soft tissue measurements were retrospectively analyzed digitally.
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