Pigmented villonodular synovitis (PVNS) is a rare, benign, idiopathic proliferative disorder of the synovium that results in villous or nodular formation in joints, tendon sheaths, and bursae. The disease can be localized or diffuse. Its estimated prevalence is 1.8 cases per million in the United States. Large joints, such as the knee and hip, are commonly affected. Patients with this condition typically present with symptoms of mild discomfort and associated stiffness of the involved joint; however, the spectrum of presentations is broad. We present a case of an otherwise healthy 40-yr-old man who presented for evaluation of stiffness and pain in the anterior hip. His initial presentation, work-up, and course will be discussed, along with a brief review of the literature.
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http://dx.doi.org/10.1097/01.phm.0000150794.33166.3a | DOI Listing |
Narra J
December 2024
Department of Orthopedic dan Traumatology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Synovial chondromatosis is a rare disorder characterized by cartilaginous growths within the joint lining, often confused with conditions like pigmented villonodular synovitis and rheumatoid arthritis. Primary treatment typically involves surgical synovectomy to remove the affected tissue and loose bodies. Documented cases are limited globally.
View Article and Find Full Text PDFJ Orthop Case Rep
January 2025
Department of Orthopaedics, Bharatratna Dr. Babasaheb Ambedkar Municipal General Hospital, Mumbai, Maharashtra, India.
Introduction: A form of tenosynovial giant cell tumors (GCTs) that diffusely affects the soft tissue lining of joints and tendons is called pigmented villonodular synovitis or PVNS. About equal percentages of men and women are often affected, and it typically affects young individuals. The most typical sites of PVNS are the knee and ankle, making PVNS of the wrist a rare presentation.
View Article and Find Full Text PDFRev Bras Ortop (Sao Paulo)
November 2024
Serviço de Ortopedia e Traumatologia, Hospital Santa Rita de Cássia, Vitória, ES, Brasil.
Pigmented villonodular synovitis (PVNS) is rare in the shoulder, with few descriptions in the literature. We present the case of a 58-year-old female patient with no history of trauma. The patient reported pain for 2 months with no limb irradiation and presented lifting strength loss and progressive limitation of active and passive mobility.
View Article and Find Full Text PDFExpert Rev Anticancer Ther
December 2024
Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI, USA.
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