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Amyopathic Dermatomyositis with a Rapidly Progressing Interstitial Pneumonia.
Eur J Case Rep Intern Med
November 2024
Department of Lung Diseases and Thoracic Surgery, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Background: Clinically amyopathic dermatomyositis (CADM) is a rare subtype of idiopathic inflammatory myositis often linked with the presence of autoantibodies targeting melanoma differentiation-associated protein 5 (MDA5). Patients with CADM are at increased risk of developing rapidly progressing interstitial lung disease, which significantly increases both morbidity and mortality compared to other forms of inflammatory myopathies. While there is no standardized treatment regimen, current therapeutic strategies are generally focused on combination immunosuppressive therapies.
View Article and Find Full Text PDFExploring weight management beliefs during the menopausal transition (ME-WEL project): A qualitative comparative study based on Health Belief Model.
Br J Health Psychol
February 2025
William James Center for Research, Ispa - Instituto Universitário, Lisboa, Portugal.
Objectives: While most women experience weight gain during the menopausal transition, a subset successfully maintains a healthy weight. This study explores the determinants influencing different weight experiences during the menopausal transition, using the Health Belief Model (HBM).
Design: Qualitative design.
Graft ischemia post cell transplantation to the brain: Glucose deprivation as the primary driver of rapid cell death.
Neurotherapeutics
January 2025
School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK; Leibniz-Institut für Polymerforschung Dresden, Max Bergmann Center of Biomaterials Dresden, Hohe Straße 6, D-01069 Dresden, Germany. Electronic address:
Replacing cells lost during the progression of neurodegenerative disorders holds potential as a therapeutic strategy. Unfortunately, the majority of cells die post-transplantation, which creates logistical and biological challenges for cell therapy approaches. The cause of cell death is likely to be multifactorial in nature but has previously been correlated with hypoxia in the graft core.
View Article and Find Full Text PDFProgress towards the elimination of trachoma as a public health problem in four counties of Eastern Equatoria State, Republic of South Sudan.
Trop Med Int Health
January 2025
Trachoma Control Program, The Carter Center, Atlanta, Georgia, USA.
Background: Trachoma is targeted by the World Health Organization (WHO) for elimination as a public health problem by 2030. Trachoma impact surveys using standardised methodology are recommended to monitor progress towards elimination and to determine eligibility for continued surgery, antibiotics, facial cleanliness, and environmental improvement (SAFE) interventions. From 2007 to 2015, four counties of Eastern Equatoria State, South Sudan, received three to five rounds of mass drug administration with antibiotics.
View Article and Find Full Text PDFIn vivo efficacy of a stabilized Vitamin C-based serum at pH 6 on some ageing facial signs of women of different ages and phototypes.
Int J Cosmet Sci
January 2025
L'Oréal Research & Innovation, Chevilly-Larue, France.
Objective: To assess, clinically and instrumentally, the efficacy of a stabilized 12% Vitamin C (VC)-based serum (pH 6) on skin photoageing of women of various age and phototype.
Materials And Methods: Eighty women, with Phototypes I to VI, of various age (45-70y) living in Mauritius, participated in an open, uncontrolled study. After a two-week period of washout, they applied the Vitamin C-based serum twice a day for 2 months onto their whole face as well as a hydrating cream every evening to ensure a comparable skin hydration level in all subjects.
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