AI Article Synopsis

  • A low molecular weight cationic peptide from Robinia pseudoacacia seeds showed in vitro antibacterial activity against seven different bacteria.
  • The peptide inhibited bacterial growth with effective concentrations needed for 50% inhibition ranging from 20 to 120 microg ml(-1).
  • Staphylococcus aureus was the most sensitive to the peptide, while Escherichia coli displayed minimal response; the antibacterial effect was reduced when CaCl2 was added to the culture medium.

Article Abstract

A low molecular weight cationic peptide was isolated from Robinia pseudoacacia seed and tested in vitro against seven bacteria (Corynebacterium michiganense, Staphylococcus aureus, Bacillus subtilis, Erwinia carotovora subsp. carotovora, Pseudomonas syringae pv syringae, Xanthomonas campestris pv campestris, and Escherichia coli). The peptide inhibited the growth of the tested strains. The effective concentrations required for 50% inhibition of bacterial growth ranged between 20 and 120 microg ml(-1) protein. S. aureus was found to be the most sensitive strain, however, E. coli was not affected much when compared with others. Reduction of antibacterial activity of the peptide with CaCl2 addition into the growth medium was also observed.

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http://dx.doi.org/10.1016/j.fitote.2004.10.020DOI Listing

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