Cogan Sindrome is described as the association of non-syphilic interstitial keratitis with vestibulo-auditory symptoms in its typical form. We are reporting a case corresponding to a 32 years old male who consulted at first place for ophthalmic clinic and, two months later, affected of bilateral neurosensorial hearing loss with tinnitus and vestibular dysfunction. In spite of the corticoid treatment our patient has not improved. His hearing disorder was even worse after one year-follow up. A bibliographic review has been performed related to this pathology whose etiology is still unknown.
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JAMA Health Forum
January 2025
School of Nursing, Duke University, Durham, North Carolina.
BioData Min
January 2025
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.
Background: The mechanistic pathways that give rise to the extreme symptoms exhibited by rare disease patients are complex, heterogeneous, and difficult to discern. Understanding these mechanisms is critical for developing treatments that address the underlying causes of diseases rather than merely the presenting symptoms. Moreover, the same dysfunctional series of interrelated symptoms implicated in rare recessive diseases may also lead to milder and potentially preventable symptoms in carriers in the general population.
View Article and Find Full Text PDFArch Rehabil Res Clin Transl
December 2024
Department of Clinical Research and Leadership, George Washington University School of Medicine and Health Sciences, Washington, DC.
Objective: To examine associations among the time and content of rehabilitation treatment with self-care and mobility functional gain rate for adults with acquired brain injury.
Design: Retrospective cohort study using electronic health record and administrative billing data.
Setting: Inpatient rehabilitation unit at a large, academic medical center.
Lancet
January 2025
Internal Medicine Department, Delta Hospital, CHIREC & Université Libre de Bruxelles, Brussels, Belgium.
J Clin Neurol
January 2025
Dizziness Center, Clinical Neuroscience Center, Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.
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