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Preparation of Hybrid Molecularly Imprinted Polymers Based on 3-Triethoxysilylpropyl Methacrylic Amide for Solid-Phase Extraction of Gatifloxacin From Lake Water.
J Sep Sci
March 2025
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, People's Republic of China.
A novel molecularly imprinted polymer (MIP) against gatifloxacin based on a hybrid monomer (3-triethoxysilylpropyl methacrylic amide, APTES-MAA) was reported. In this study, the imprinted monolith was synthesized with gatifloxacin as template, ethylene glycol dimethacrylate (EGDMA) as cross-linker, and APTES-MAA as functional monomer in a mixture of acetonitrile and isooctane as porogen via an optimization based on density functional theory (DFT). The polymers were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, and mercury porosimetry.
View Article and Find Full Text PDFWhy did it take forty years to uncover long-term fluoroquinolone associated toxicities?
Eur J Intern Med
March 2025
Floyd and Delores Jones Cancer Institute at Virginia Mason and the Division of Hematology, University of Washington, Seattle, WA, USA.
Doctors' preferences in the choice of antibacterial drugs in pregnant women (PIKAP study).
Int J Risk Saf Med
March 2025
Medical Center "Azbuka Zdorovya", Belgorod, Russia.
BackgroundThe use of rational and safe antibiotic therapies for pregnant women remains an important issue within the medical community.ObjectiveTo analyze the preferences in the choice of antimicrobial drugs (AMD) among obstetricians-gynecologists of Central Russia in treatment of infectious diseases in pregnancy.MethodsThis is anonymous survey of obstetrician and gynecology specialists conducted in Central Russia between September 1st, and November 30th, 2017.
View Article and Find Full Text PDFA guide to empirical management of urinary tract infection in outpatient setting in a tertiary care institute: A study from Western India.
J Postgrad Med
March 2025
Department of Microbiology, Mahatma Gandhi Medical University of Medical Sciences and Technology Jaipur, Rajasthan, India.
Introduction: Urinary tract infections make up a major proportion of infections encountered in outpatient setting in hospitals. Treatment is largely based on the epidemiology of locally prevalent flora. Selection of an appropriate antibiotic is crucial, as inappropriate use could contribute to an alarming rise in antimicrobial resistance.
View Article and Find Full Text PDFDrug susceptibility of uropathogens isolated from patients treated at the Mazovian Specialized Hospital in Radom.
Acta Biochim Pol
March 2025
Department of Laboratory Diagnostics, Military Institute of Medicine-National Research Institute, Warsaw, Poland.
Urinary tract infections (UTI) are a significant problem among populations worldwide. It is mainly associated with the increasing incidence of recurrence, complications and the increasing drug resistance of uropathogens. The aim of this study was to demonstrate the prevalence of resistance among pathogens causing urinary tract infections.
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