To assess the risk factors of mycotic infection on the gastric mucosa (GM) in patients with gastric peptic ulcer, 34 patients who had much mycelium on the bottom of the defect and 122 patients without fungal infection were examined in detail. The occurrence of mycotic infection in patients with ulcerative defects was associated with a variety of both local (the depth, number, large sizes of defects, diminished gastric acid-producing ability) and total (age, trophological insufficiency, iron-deficiency anemia, oral mycotic disease, autonomic dysfunction) factors. Mycotic involvement of ulcerative defects is secondary and regarded as a focal manifestation of mycotic infection. The likely impact of mycotic infection on the quality of ulcerative defect scarring makes us consider whether antimycotic agents should be added to antiulcerative therapy.

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