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Mechanisms of increased pain discrimination by contingent reinforcement: a perceptual decision-making and instrumental learning account.
Pain
January 2025
Integrative Spinal Research Group, Department of Chiropractic Medicine, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Recent evidence highlights that monetary rewards can increase the precision at which healthy human volunteers can detect small changes in the intensity of thermal noxious stimuli, contradicting the idea that rewards exert a broad inhibiting influence on pain perception. This effect was stronger with contingent rewards compared with noncontingent rewards, suggesting a successful learning process. In the present study, we implemented a model comparison approach that aimed to improve our understanding of the mechanisms that underlie thermal noxious discrimination in humans.
View Article and Find Full Text PDFAn integrated multiphase dynamic genome-scale model explains batch fermentations led by species of the genus.
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Biosystems and Bioprocess Engineering, IIM-CSIC, Vigo, Spain.
During batch fermentation, a variety of compounds are synthesized, as microorganisms undergo distinct growth phases: lag, exponential, growth-no-growth transition, stationary, and decay. A detailed understanding of the metabolic pathways involved in these phases is crucial for optimizing the production of target compounds. Dynamic flux balance analysis (dFBA) offers insight into the dynamics of metabolic pathways.
View Article and Find Full Text PDFTouch-driven advantages in reaction time but not in performance in a cross-sensory comparison of reinforcement learning.
Heliyon
January 2025
Centre for Tactile Internet with Human-in-the-Loop (CeTI), 6G Life, Technische Universität Dresden, Germany.
Recent research has highlighted a notable confidence bias in the haptic sense, yet its impact on learning relative to other senses remains unexplored. This online study investigated learning behaviour across visual, auditory, and haptic modalities using a probabilistic selection task on computers and mobile devices, employing dynamic and ecologically valid stimuli to enhance generalisability. We analysed reaction time as an indicator of confidence, alongside learning speed and task accuracy.
View Article and Find Full Text PDFModeling of magnetic vestibular stimulation experienced during high-field clinical MRI.
Commun Med (Lond)
January 2025
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Background: High-field magnetic resonance imaging (MRI) is a powerful diagnostic tool but can induce unintended physiological effects, such as nystagmus and dizziness, potentially compromising the comfort and safety of individuals undergoing imaging. These effects likely result from the Lorentz force, which arises from the interaction between the MRI's static magnetic field and electrical currents in the inner ear. Yet, the Lorentz force hypothesis fails to explain observed eye movement patterns in healthy adults fully.
View Article and Find Full Text PDFResearch on credit risk of listed companies: a hybrid model based on TCN and DilateFormer.
Sci Rep
January 2025
College of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao, 266510, China.
The ability to assess and manage corporate credit risk enables financial institutions and investors to mitigate risk, enhance the precision of their decision-making, and adapt their strategies in a prompt and effective manner. The growing quantity of data and the increasing complexity of indicators have rendered traditional machine learning methods ineffective in enhancing the accuracy of credit risk assessment. Consequently, academics have begun to explore the potential of models based on deep learning.
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