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Clinical inertia in onychomycosis treatment: results from the Illuminating Dialogues and Insights in Onychomycosis Management (IDIOM) survey.
J Dermatol
January 2025
Sato Pharmaceutical Co., Ltd, Tokyo, Japan.
Article Synopsis
- Onychomycosis is a persistent fungal nail infection that can spread and negatively impact a person's ability to walk and their quality of life, making treatment crucial, especially through long-term topical therapies.
- A study revealed that many patients are unhappy with the effectiveness of their topical treatments—over half saw no clear improvement after more than two years—and most wished to explore different options, yet few discussed this with their doctors.
- There is a notable disconnect in communication between patients and dermatologists regarding treatment efficacy, leading to a lack of adjustments in therapy despite patient dissatisfaction, highlighting the need for better collaboration in managing onychomycosis.
Cancer research provides a model for advancing clinical trials in dementia in the era of disease-modifying Alzheimer's-type dementia therapies.
Alzheimers Res Ther
August 2024
Department of Pathology and Laboratory Medicine, University of Kentucky, Rm 575 Lee Todd Bldg, 789 S. Limestone Ave, Lexington, KY, 40536, USA.
Article Synopsis
- Dementia and cancer are increasingly common, complex health issues, with cancer research making significant strides in treatment while dementia research lags behind.
- Current cancer trial practices emphasize the importance of allowing patients to choose between standard and experimental treatments despite risks, a concept that could be applied to dementia research given its high morbidity and mortality rates.
- Fear and concern about dementia are widely recognized, suggesting a need to rethink restrictions on patient participation in clinical trials, which could potentially provide benefits even to those in placebo groups.
Oxygen-Mediated (0D) CsPbX Formation during Open-Air Thermal Processing Improves Inorganic Perovskite Solar Cell Performance.
ACS Nano
July 2024
Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Queensland 4072, Australia.
The desire to commercialize perovskite solar cells continues to mount, motivating the development of scalable production. Evaluations of the impact of open-air processing have revealed a variety of physical changes in the fabricated devices─with few changes having the capacity to be functionalized. Here, we highlight the beneficial role of ambient oxygen during the open-air thermal processing of metastable γ-CsPbI-based perovskite thin films and devices.
View Article and Find Full Text PDFManagement Considerations for Air Medical Transport Programs Transfusing RhD-Positive Red Blood Cell-Containing Products to Females of Childbearing Potential.
Air Med J
June 2024
Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA; Blizard Institute for Neuroscience, Surgery, and Trauma, Barts and The London School of Medicine, London, UK.
Article Synopsis
- Recent discussions in trauma care have focused on damage control resuscitation, the prehospital transfusion of blood products, and the preference for whole blood instead of separate components, particularly amidst blood product shortages.
- There’s a shift in administering RhD-positive blood to females of childbearing potential (FCPs) during air medical transport, which could enhance benefits but also raises concerns about hemolytic disease of the fetus and newborn (HDFN).
- Air medical transport programs should understand HDFN risks, have a plan to communicate RhD-incompatibility to receiving facilities, and be prepared to provide necessary prophylaxis for patients affected by this practice.
Psychological experience of university students during prolonged quarantine in China: a qualitative study.
BMJ Open
March 2024
School of Nursing, Zhejiang Shuren University, Hangzhou, China
Objective: To explore the psychological experiences of university students in prolonged quarantine during the COVID-19 pandemic.
Design: A qualitative descriptive study based on semistructured interviews; data were analysed using a thematic topic analysis approach.
Setting: Interviews were conducted via WeChat video.
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