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Introduction: Bisphosphonates are commonly used to prevent osteoporotic fractures. Many randomized controlled trials have proved the efficacy of bisphosphonates, showing their ability to increase bone mineral density and decrease the risk of hip and vertebral fractures. Atypical, bisphosphonate-related fractures concerning the femur have been widely described and a list of primary and secondary clinical and radiographic criteria are used in order to achieve diagnosis.

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The role of oxidative stress and antioxidants in older individuals with osteoporotic hip fractures.

Ulus Travma Acil Cerrahi Derg

January 2025

Department of Biochemistry, Gulhane Faculty of Pharmacy, University of Health Sciences, Ankara-Türkiye.

Background: Osteoporosis is characteristically defined as a decrease in bone density and mass, accompanied by the deterioration of bone structure, which increases bone fragility and the risk of fractures. Osteoporosis frequently develops with age. In high-risk populations, oxidative damage is a common pathological condition.

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[Not Available].

Tunis Med

December 2024

Orthopaedic Department, Fattouma Bourguiba Hospital, Monastir Faculty of Medicine, University of Monastir, Tunisia.

Objectives: To evaluate survival after osteoporotic fractures of the upper femur and determine its associated factors.

Methods: Cross-sectional study of patients hospitalized for fractures of the upper end of the femur during 2020 at Monastir University Hospital. Outcome was determined up to 2 years.

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Osteoporotic hip fractures (HFs) in the elderly are a pertinent issue in healthcare, particularly in developed countries such as Australia. Estimating prognosis following admission remains a key challenge. Current predictive tools require numerous patient input features including those unavailable early in admission.

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Background: Recently researches have reported that miRNA and its target genes are associated with osteoporosis. MiRNA and mRNA might be potential diagnostic markers for osteoporosis.

Purposes: The aim of this study is to explore the potential miRNA and mRNA markers by bioinformatics method and clinical analysis.

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