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Brain Spine
March 2024
Consultant Orthopaedic Surgeon, San Carlo Borromeo Hospital, Via Pio II 3, Milano, Italy.
Introduction: Bisphosphonates are commonly used to prevent osteoporotic fractures. Many randomized controlled trials have proved the efficacy of bisphosphonates, showing their ability to increase bone mineral density and decrease the risk of hip and vertebral fractures. Atypical, bisphosphonate-related fractures concerning the femur have been widely described and a list of primary and secondary clinical and radiographic criteria are used in order to achieve diagnosis.
View Article and Find Full Text PDFUlus Travma Acil Cerrahi Derg
January 2025
Department of Biochemistry, Gulhane Faculty of Pharmacy, University of Health Sciences, Ankara-Türkiye.
Background: Osteoporosis is characteristically defined as a decrease in bone density and mass, accompanied by the deterioration of bone structure, which increases bone fragility and the risk of fractures. Osteoporosis frequently develops with age. In high-risk populations, oxidative damage is a common pathological condition.
View Article and Find Full Text PDFTunis Med
December 2024
Orthopaedic Department, Fattouma Bourguiba Hospital, Monastir Faculty of Medicine, University of Monastir, Tunisia.
Objectives: To evaluate survival after osteoporotic fractures of the upper femur and determine its associated factors.
Methods: Cross-sectional study of patients hospitalized for fractures of the upper end of the femur during 2020 at Monastir University Hospital. Outcome was determined up to 2 years.
PLOS Digit Health
January 2025
Department of Geriatric Medicine, The Canberra Hospital, ACT Health, Canberra, Australia.
Osteoporotic hip fractures (HFs) in the elderly are a pertinent issue in healthcare, particularly in developed countries such as Australia. Estimating prognosis following admission remains a key challenge. Current predictive tools require numerous patient input features including those unavailable early in admission.
View Article and Find Full Text PDFPLoS One
December 2024
Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Background: Recently researches have reported that miRNA and its target genes are associated with osteoporosis. MiRNA and mRNA might be potential diagnostic markers for osteoporosis.
Purposes: The aim of this study is to explore the potential miRNA and mRNA markers by bioinformatics method and clinical analysis.
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